非共价键交联海藻酸钠水凝胶的制备与性能  

Preparation and Property of Sodium Alginate Hydrogel Crosslinked by Non-Covalent Bonds

作　　者：康祺 于炜婷[2] 吴叶[1] 刘袖洞[1] 马小军[2] 

机构地区：[1]大连大学环境与化学工程学院,大连116622 [2]中国科学院大连化学物理研究所,大连116023

出　　处：《化学通报》2015年第3期236-236,共1页Chemistry

摘　　要：天然多糖海藻酸钠制备的水凝胶具有优越的生物相容性和生物组织相似性,作为生物医用材料在药物控制释放、组织工程支架、抗菌材料及创伤敷料等领域发挥着越来越大的作用。本文在介绍海藻酸钠物化性质的基础上,重点综述了非共价键交联(静电作用、氢键、范德华力、亲疏水作用等)海藻酸钠水凝胶的制备方法以及性能表征方法,最后讨论了制备方法及性能表征研究中的一些需要解决的问题。Sodium alginate hydrogel has been widely used as biomedical materials in drug delivery system,tissue engineering scaffolds,antibacterial material and wound dressing,due to their superior biocompatibility and resemblance to biological tissues.Based on the brief introduction of physicochemical properties of sodium alginate,the progress in preparation methods on sodium alginate hydrogel crosslinked by non-covalent bonds is summarized including electrostatic interaction,hydrogen bonds,van der Waals forces and hydrophobic effects,etc. Meantime,the characterization methods of properties of sodium alginate hydrogel are also concerned. Finally,some problems related to the development of preparation and characterization methods are discussed.

关 键 词：海藻酸钠 水凝胶 非共价键交联 

分 类 号：O648.17[理学—物理化学]