不同麻醉下手术病人血浆皮质醇浓度变化的观察  

The observation of cortisol plasma levels in surgical patients under different anesthesia

作　　者：蒋昭祥[1] 朱立人 张鹤[1] 刘正德[1] 邵小玲 

机构地区：[1]安徽皖南医学院弋矶山医院麻醉科

出　　处：《临床麻醉学杂志》1989年第2期70-72,共3页Journal of Clinical Anesthesiology

摘　　要：麻醉-手术-失血可引起机体系列应激反应,血中ACTH和皮质醇浓度几乎在很短时间内上升。本文旨在通过针麻、颈丛阻滞、硬膜外阻滞,静脉复合麻醉下手术病人血浆皮质醇的测定,以了解病人对麻醉、手术创伤的应变能力。与此同时,选择适当麻醉方法以维护有利的生理调节功能,尽量减少或避免因这种防御作用而产生的不利影响。A dynamic plasma cortisol levels were studied in 47 surgical patients by means of radioimmunoassay during anesthesia and operation,the anesthesia techniques wore carried out including acupuncture analgesia, cervical plexus block,epidural block and combined intravenous anesthesia. Blood specimens are taken respectively for determination at 30 min after rest and before anesthesia, 15-30 min after anesthesia, 0.5-1h after the starting of surgery, at the end of operation and 24h after operation. The results showed that the plasma cortisol levels increased markedly in the periods of post-anesthesia, immediacy after surgery, at the end of operation and post-operatively, the statistical difference was extremely significant in other 3 groups (p<0.01) except epidural block. Discussion was made in concerning with the importance of monitoring the plasma cortisol level perioperatively regardless of any anesthesia technique.

关 键 词：麻醉方法 血浆 皮质醇浓度 

分 类 号：R614.1[医药卫生—麻醉学]