早产影响因素的多分类Logistic回归分析  

Factors Associated with Preterm Delivery: A Multinomial Logistic Regression Analysis

作　　者：张东峰[1] 姜秀波[1] 李红彩 曹玉民[3] 吕秀翠[3] 

机构地区：[1]青岛大学医学院预防医学教研室,青岛市266021 [2]青岛市海慈医疗集团中医妇科 [3]青岛市第八人民医院妇产科

出　　处：《中国医院统计》2004年第2期102-105,共4页Chinese Journal of Hospital Statistics

基　　金：山东省科技厅科研基金项目 ( 1999BB1CBA1)

摘　　要：目的　探讨早产儿发生的危险因素。方法　采用病例对照研究法对 2 2 7名早产儿 (孕周 <33周 73人 ,33～ 36周 15 4人 )和 75 0名对照组进行相关因素调查 ,用多分类Logistic回归分析法进行危险因素分析。结果与分娩孕周 <33周早产儿有关的因素是 :母亲孕前体质指数≥ 2 8者、有人工流产史、孕早期发热、母亲文化水平为小学及以下者 ,首次产前检查血红蛋白低于 10 0g/L者、尿蛋白和尿糖阳性等因素是分娩孕周 <33周早产儿的危险因素。与分娩孕周在 33～ 36周早产儿有关的因素有 :母亲分娩年龄大于 35岁、母亲孕期吸烟及饮酒、年家庭收入低及父亲吸烟等因素。父亲职业为农民、多胎妊娠、孕期精神刺激、产前检查次数少、前置胎盘和妊高症等因素是二者的共同危险因素。结论　早产是多种因素联合作用的结果 ,应采取综合性措施降低早产儿的发生率。Objective To survey the risk factors of preterm delivery.Methods 227 preterm delivery infants (very preterm birth <33 weeks:73, moderate preterm births 33～36weeks: 154) and 750 controls were investigated by use of questionnaire. Multinomial logistic regression analysis was applied to analyze the related risk factors for preterm delivery.Results The risk factors which were related to very perterm births <33 weeks were mothers' BMI≥28 before pregnancy, women with less education compared to women a higher education, Hb<100g/L, glucose in urine and urinary protein which were positive in the first check. The risk factors which were related 33～36 week delivery were maternal age ≥35, maternal smoking and drinking during pregnancy, low family income, and father smoking . The factors, which were related to <33 weeks delivery and 33～36 weeks delivery were father who were peasants, twins, psychosocial stress in pregnancy, little prenatal care, placenta previa, and pregnancy-induced hypertension syndrome.Conclusion Preterm delivery were caused by many factors. Comprehensive measures should be taken to reduce possibility of preterm delivery infants.

关 键 词：早产 多分类Logistic回归分析 危险因素 婴儿 多胎妊娠 前置胎盘 

分 类 号：R714.21[医药卫生—妇产科学] R195.4[医药卫生—临床医学]