急性心肌梗塞后血栓素 B_2和6酮前列腺素 F_(1α)的演变及临床意义  

The role of dynamic change of plasma TXB_2 and 6-keto-PGF_(1α) levels after acute myocardial infarction

作　　者：丁怀翌[1] 龚兰生[1] 林淑英[1] 过鑫昌[1] 蔡伟菁[1] 吴春芳[1] 蔡秋艳[1] 

机构地区：[1]上海第二医科大学附属瑞金医院内科

出　　处：《临床心血管病杂志》1989年第1期12-14,共3页Journal of Clinical Cardiology

摘　　要：对51例急性心肌梗塞后患者进行了平均22.1±7月的随访,有8例死亡。虽死亡组与存活组比较,入院初3次血栓素 B_2(TxB_2)均值较高,6酮前列腺素 F_(1α)(6酮 PGF_(1α))均值较低,但无统计学显著性差异.还观察了2年中 TXB_2与6酮 PGF_(1α)的演变,发现后者呈稳步下降,而前者的演变可分为稳定组与不稳定组,对之进行了临床分析。In 51 cases of acute myoeardial infarction,the plasma levels of TXB_2 and 6- Keto-PGF_(1α)were examined serially to evaluate the role of tbeir dynamic changes.During 22.1±7 months follow-up period,8 died.The average values of TXB_2 and 6-keto-PGF_(1α)of the first 3 examinations during hospital days had no significant difference between alive and non-alive groups. The average value of 6 keto-PGF_(1α)was highest on the first hospital day,thon decreasing gradually in the follow-up studies and below normal level after 6 months. The average valve of TXB_2 was also highest on the first hospital day.In the follow-up studies,part of the patients(stable group)showed their TXB_2 values decreasing gradually,but others(unstable gloup)showed the values floating strongly even after 12 months.The latter gloup was predisposed to angina pectoris and arrhythmia.Then average ejection rraction was lower than that of stable group.

关 键 词：心肌梗塞 血栓素B2 前列腺素 

分 类 号：R542.22[医药卫生—心血管疾病]