急性起病的非甲非乙型病毒性肝炎的病原分析  

Acute onset of Non-A, Non-B viral hepatitis:An etlological analysis

作　　者：朱幼芙[1] 孟庆华[1] 杨守昌[1] 何海棠[1] 周荣[1] 梁炽森[1] 骆抗先[1] 

机构地区：[1]南方医院传染病科

出　　处：《第一军医大学学报》1993年第1期12-15,共4页Journal of First Military Medical University

摘　　要：对HBsAg(一)、IgM抗HAV(一)临床诊断为急性非甲非乙肝炎63例,进行了病原学鉴定。以聚合酶链反应(PCR)检测HBV DNA,HCV RNA,并检测了IgM抗HBc和抗HCV血清抗体。诊断为急性丙型肝炎15例(23.8％),急性乙型肝炎20例(31.7％),慢性HBV携带者急性活动19例(30.2％),乙、丙型混合肝炎2例(3.2％),病原不明7例(11.1％)。结果表明在临床所谓的急性非甲非乙肝炎中,急性和慢性乙型肝炎仍占多数。Further etilogical identification was carried out on 63 cases with negative hepatitis B surface antigen and IgM antibody against hepatitis A virus; they were diagnosed as acute hepatitis non-A non-B clinically.Viruses were dete-cted by polymerase chain reaction, serum IgM antibody to hepatitis B core by the Abbott kit, and antibody to hepatitis C virus by an EIA using synthesized oligopeptide CP-36.The results revealed that 15 cases ( 23.8% ) were acute hepatitis C, 20 ( 31.7% ) acute hepatitis B, 19 ( 30.2% ) acute episode of chronic asymptomatic hepatitis B virus carriers, two mixed hepatitis B and C, and seven remained aetiologically unknown.Among the so-called acute hepatitis non-A, non-B clinically the majority of cases were still acute and chronic hepatitis B.

关 键 词：丙型肝炎 病原学 

分 类 号：R512.630.3[医药卫生—内科学]