中药复方S-抗毒合剂对家兔免疫球蛋白的影响研究  

Effect of Chinese medicine S-Kangdu compositus on lmmunoglobulins in Rabbit

作　　者：张云美[1] 李福英 钱光玲 吴登虎[2] 潘永全 毕小云[4] 

机构地区：[1]重庆医科大学中医药学院,重庆400050 [2]重庆动物园动物医院,重庆4000503 [3]重庆医科大学实验动物中心,重庆400016 [4]重庆医科大学附属第一医院,重庆400016

出　　处：《医学动物防制》2004年第5期273-275,共3页Journal of Medical Pest Control

基　　金：重庆市科委基金资助项目 (编号 0 3 -7998) ;重庆市卫生局基金资助项目 (渝中医 [2 0 0 3 ] 3 2号)

摘　　要：目的　观察中药复方S -抗毒合剂对家兔免疫球蛋白IgG、IgM、和IgA的影响。方法　家兔饲喂含3%复方S -抗毒合剂的日粮 ,然后在 1、3、5、7、14、2 1、2 8日时采血进行免疫球蛋白分析。结果　中药实验组与对照组比较 ,IgG和IgA有显著差异 ;且在 1- 14日内中药实验组免疫球蛋白呈明显的双向调节变化 ;在 14 - 2 8日IgG显著增高 ,IgM、和IgA显著降低。结论　中药复方S -抗毒合剂对免疫球蛋白IgG、IgM、和IgA有明显的影响 ;并具有双向调节免疫球蛋白的作用。Objctive: To examine the effects of Chinese medicine S-Kangdu compositus on IgG, IgM, and IgA of rabbits. Methods: Rabbits were raised with feed containing 3% S-Kangdu compositus , and blood samples were collected on day 1, 3, 5, 7, 14, 21, 28 for analysis of immunoglobulins. Results: There is sighificart difference in the level of IgG and IgA between treated and controled groups. Immunoglobulins were regulated dually between 1 to 14 days in treated group. IgG increaded dramatically between 14 to 28 days while IgM and IgA decreased predominently. Conclusions: The Chinese medicine S-Kangdu compositus could exert significant effects on dual regulation of immunoglobulin IgG, IgM, and IgA.

关 键 词：中药复方S一抗毒合剂 家兔 免疫球蛋白 双向调节 禽类疾病 血清抗体 

分 类 号：R28[医药卫生—中药学]