东菱迪芙治疗突发性耳聋的临床疗效观察  

The therapeutic effect of batroxobin in the treatment of sudden deafness

作　　者：王向阳[1] 石丽亚[1] 徐珀[1] 

机构地区：[1]中国人民解放军第四六六医院,北京100089

出　　处：《中华耳科学杂志》2004年第2期133-134,共2页Chinese Journal of Otology

摘　　要：目的观察东菱迪芙(DF-521)对突发性耳聋的临床疗效;方法60例突发性耳聋患者随机分为两组。试验组(DF-521组)静脉点滴东菱迪芙首次10BU,隔日给5BU,连用4次一个疗程;对照组静滴葛根素400mg,每日1次,10天一个疗程。结果试验组:总有效率80%。对照组:总有效率73郾3%。两组之间有显著差异(P<0郾01)。两组之间治疗后血流变学和纤维蛋白原有显著差异(P<0郾01)。结论东菱迪芙治疗突发性耳聋是一种比较理想的药物。Objective To observe the efficiency of Batroxobin (DF-521) in sudden deafness. Methods 60 cases (64 ears) with sudden deafness were divided into 2 groups randomly. The DF-521 group received Batroxobin 10BU at the first time and 5BU every other day by intravenous drip. One course consisted of 4 times. The control group received Puerarin 400mg every day for 10 times by intravenous drip. Results The effective rate of DF-521 group and control group were 80% and 73.3%, respectively. The difference was significant (P<0.01). Hemorheology and fibrinogen were significant difference between the two groups(P<0.01) after treatment. Conclusion DF-521 is effective in treating sudden deafness.

关 键 词：东菱迪芙 治疗 突发性耳聋 静脉点滴 葛根素 

分 类 号：R764.437[医药卫生—耳鼻咽喉科]