Comparison of Catalytical and Biological Activities for Substituted Polyoxotungstates Containing Ti and CpTi  

作　　者：LIU Jing-fu WANG Xiao-hong 等 

机构地区：[1]InstituteofPolyoxometalateChemistry,FacultyofChemistry,NortheastNormalUniversity,Changchun130024,P.R.China [2]InstituteofPolyoxometalateChemistry,FacultyofChemistry,NortheastNormalUnivers

出　　处：《Chemical Research in Chinese Universities》2003年第1期20-23,共4页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China(No.39970 82 4 )

摘　　要：The effect of the functionallization of POMs on their properties was examined by the comparison between both titanium and its corresponding cyclopentadienyl subsituted polyoxocomplexes. The polarographic half wave potential of the complexes indicated that the effect of the functionallization of POMs increased the oxidizing ability of the polyoxoanions. The inhibitory effects of the CpTi polyoxocomplexes on tumor cells are higher than those of the corresponding titanium polyoxocomplexes, and the toxicity of the former is lower than that of the latter. The oxygenation reactions of cyclohexene, styrene, trans stilbene and maleic acid with PhIO or hydrogen peroxide(30% aqueous solution) catalyzed respectively by Ti and CpTi polyoxocomplexes were compared.The effect of the functionallization of POMs on their properties was examined by the comparison between both titanium and its corresponding cyclopentadienyl subsituted polyoxocomplexes. The polarographic half wave potential of the complexes indicated that the effect of the functionallization of POMs increased the oxidizing ability of the polyoxoanions. The inhibitory effects of the CpTi polyoxocomplexes on tumor cells are higher than those of the corresponding titanium polyoxocomplexes, and the toxicity of the former is lower than that of the latter. The oxygenation reactions of cyclohexene, styrene, trans stilbene and maleic acid with PhIO or hydrogen peroxide(30% aqueous solution) catalyzed respectively by Ti and CpTi polyoxocomplexes were compared.

关 键 词：POLYOXOMETALATE Titanium substituted polyoxotungstate 183  W NMR Antitumor activity 

分 类 号：R979.1[医药卫生—药品] R914[医药卫生—药学]