利多卡因雾化吸入佐治小儿毛细支气管炎疗效观察  

Ultrasonic atomization inhalation of lidocainefor the assistant treatment of bronchiolitis

作　　者：王桂芝[1] 陈煌煌[1] 连文昌[1] 

机构地区：[1]莆田学院附属医院儿科,福建莆田351100

出　　处：《泰山医学院学报》2004年第2期132-134,共3页Journal of Taishan Medical College

摘　　要：目的　观察利多卡因超声雾化吸入佐治毛细支气管炎的疗效。方法　 10 5例毛细支气管炎患儿随机分为两组 ,对照组 5 3例 ,治疗组 5 2例 ;两组常规予以抗感染、抗病毒、吸氧等处理 ,治疗组在雾化液中加入 2 %利多卡因 3～ 5ml雾化吸入 ,每日 2～ 3次。观察两组治疗前后血气、心率、呼吸频率变化及喘息缓解、哮鸣、咳嗽消失时间。结果　治疗组、对照组血气、心率、呼吸频率均有显著性差异 (P <0 0 5 )。喘息缓解、哮鸣、咳嗽消失时间明显缩短 (P <0 0 5 )。治愈率治疗组与对照组有显著差异 (P <0 0 1)。结论　利多卡因超声雾化吸入是佐治毛细支气管炎安全有效的方法之一。Objective: To observe the efficacy of ultrasonic atomization inhalation of lidocaine for the assistant treatment of bronchiolitis. Methods: 105 cases of paediatic patients with bronchiolitis were divided into two groups randomizedly, with 53 cases in control group, 52 cases in treatment group. All patients were treated with oxygen inhalation and antiinfective and/or antivirus agents, but patients in treatment group with further treatment of ultrasonic atomization inhalation of 3～5 ml of 2% lidocaine solution 2～3 times daily. The blood-gas analysis、heart rate and expiration rate changes were observed before and after therapy, the duration of wheeze relieved, asthma and cough disappeared. Results: There were significant difference in blood-gas analysis, heart rtes and expiration rates after treatment between two groups(P<0.05). The duration of wheeze relieved, asthma and cough disappeared. After treatment were significantly shortened in treatment group(P<0.05), there was significant difference in the cure rate between two groups also(P<0.01). Conclusion: Ultrasonic atomization inhalation of lidocaine for assistant treatment of bronchiolitis in paediatric patients is safe and effective.

关 键 词：利多卡因 超声雾化吸入 毛细支气管炎 

分 类 号：R725.6[医药卫生—儿科]