二线抗痨药的降阶梯治疗对复治重症肺结核的疗效评价  

Evaluation of Effect of De-escalation Therapy with Second-line Anti-TB Drugs on Retreated Serious Pulmonary Tuberculosis

作　　者：张耀亭[1] 韩晓光[1] 郑佳鹏[1] 

机构地区：[1]解放军第175医院肺科,福建漳州363000

出　　处：《江西医学院学报》2004年第3期39-41,共3页Acta Academiae Medicinae Jiangxi

摘　　要：目的　评价二线抗痨药降阶梯治疗对复治重症肺结核的疗效。方法　对复治重症肺结核 32 0例经二线抗痨药 2LDVThA(Am、Z、P) / 6LDVTh/ 4LDV降阶梯方案治疗 ,观察疗效及 2年内复发率。结果　疗程结束时 ,痰菌阴转率 95 .3% ,病灶显效率 91.5 % ,2年内复发率 1.4 %。结论　二线抗痨药降阶梯方案治疗复治重症肺结核 ,治愈率高 ,复发率低 。Objective To observe and evaluate the therapeutic efficacy in de-escalation treatment of retreated serious pulmonary tuberculosis with second-line anti-TB drugs.Methods Three hundred twenty patients with retreated serious pulmonary tuberculosis were treated with 2LDVTh A(Am、Z、P)/6LDVTh/4LDV.The therapeutic effect and relapse rate in 2 years were observed.Results One year late,the sputum negative conversion rate was 95.3% and the foci marked absorption rate was 91.5%. The follow-up for 2 years showed that the positive conversion rate was 1.4%.Conclusion The de-escalation therapeutic regimen with second-line anti-TB drugs is favorable to sputum relative conversion and vanishing of the foci, with lower relapse rate.

关 键 词：结核 肺 重症 二线抗痨药 降阶梯治疗 

分 类 号：R521[医药卫生—内科学]