辐照氟银肌腱的生物力学和组织形态学变化  

Biomedical and Morphological Study of γ-Irradiated Tendon Incorporated with Norfloxacin and Silver

作　　者：辛国华[1] 邹立津[1] 曾元临[1] 余於戎[1] 毛远桂[1] 

机构地区：[1]江西医学院第一附属院烧伤中心,江西南昌330006

出　　处：《江西医学院学报》2004年第3期4-5,共2页Acta Academiae Medicinae Jiangxi

基　　金：江西省卫生厅资助课题 (G0 0 0 5 19);江西省卫生厅跨世纪学科带头人资助课题 (G0 0 0 5 0 5 )

摘　　要：目的　探讨辐照氟银肌腱的生物力学性质及形态学变化。方法　肌腱随机分为 3组 :辐照氟银肌腱 (A组 ) ,深低温冷冻肌腱 (B组 )与新鲜肌腱 (C组 )。观察各组生物力学及形态学组织学的变化。结果　辐照氟银组最大载荷和抗张强度明显大于其它各组 (P <0 .0 1) ;组织形态学上各处理组均不同于正常肌腱 ,辐照氟银组光镜下几无细胞 ,纤维呈波浪形 ,深低温冷冻肌腱组细胞很少 ,纤维间距大。Objective To explore the biomechanical and morphological characters of γ-Irradiated tendon incorporated with norfloxacin and silver immersion.Methods Tendons were randomly divided into three groups:irradiated allogeneic tendon incorporated with norfloxacin and silver group(Group A),deep-frozen allogeneic tendon group(Group B)and autogeneic tendon group(GroupC).Biomechanic or histology properties were observed.Results The ultimate tensile stress of Group A was markedly greater than that of Group B and C(P<0.01).All treated tendons differed considerably from the normal tendon in histological.γ-Irradiated tendons had no cellularity, but had a larger amplitude,pitch of crimp,and wider interfibrillar spaces than normal tendons.The deep-frozen tendons also showed less cellularity and had wider interfibrillar spaces.Conclusion γ-Irradiated tendon incorporated with norfloxacin and silver immersion may be used to allogeneic grafts.

关 键 词：辐照氟银肌腱 生物力学 形态学 异体移植 低温冷冻 处理方法 

分 类 号：R622.2[医药卫生—整形外科]