AIDS-Associated Mycoplasmas Infections in Patients with Nongonococcal Urethritis and Mucopurulent Cervicitis  

非淋菌性尿道(宫颈)炎患者中与艾滋病相关的支原体感染的调查研究(英文)

作　　者：赖伟红[1] 王荷英[1] 施美琴[1] 苏晓红[1] 姜文华[1] 

机构地区：[1]中国医学科学院中国协和医科大学皮肤病研究所,南京210042

出　　处：《Chinese Journal of Sexually Transmitted Infections》2004年第1期40-43,64,65,共6页中华性传播感染杂志（英文版）

摘　　要：Background: The incidence of sexually transmittedHIV infections is rapidly increasing in China, and theprevalence of AIDS-associated mycoplasmas (includingMycoplasma genitalium, Mycoplasma penetrans, Myco-plasma pirum and Mycoplasma fermentans) infections isunknown in patients with sexually transmitted diseases.Objective: To investigate the prevalence of these 4species of AIDS-associated mycoplasmas infections inpatients with nongonococcal urethritis (NGU) andmucopurulent cervicitis (MPC).Methods: In 65 patients with NGU/MPC, detection ofM. genitalium, M. penetrans, M. pirum and M. fermentansin genital and pharyngeal specimens was performed byculture and nested polymerase chain reaction.Results: M. genitalium, M. penetrans, M. pirum and M.fermentans were identified in genital specimens from23.1% (15/65), 12.3% (8/65), 1.5% (1/65) and 0% ofpatients, respectively, and from pharyngeal samples in26.2% (17/65), 15.4% (10/65), 1.5% (1/65) and 0% ofpatients, respectively. M. genitalium was detected in bothgenital and pharyngeal samples in 10.8% (7/65) ofpatients, and M. penetrans in 4.6% (3/65) of patients. M.pirum was found in only 2 cases, and no M. fermentanswas discovered.Conclusions: This study suggests that M. genitaliumand M. penetrans infections are common in patients withNGU/MPC. M. genitalium and M. penetrans may be trans-mitted by genital-genital or oral-genital sex, and maycause urethritis and cervicitis.背景目前我国通过性传播获得的 HIV 感染正在快速增长。但在性病人群中,几种艾滋病相关的支原体感染的流行情况尚不清楚。目的了解非淋菌性尿道炎(N G U )和粘液脓性宫颈炎(MPC)患者中几种艾滋病相关的支原体的感染情况。方法用培养法和 PCR 法对 65 例 NGU/MPC 患者的生殖道标本和咽拭子标本作了生殖支原体、穿通支原体、梨支原体和发酵支原体的检测。结果生殖道生殖支原体、穿通支原体和梨支原体的检出阳性率分别为23.1%(15/65)、12.3%(8/65)和 1.5%(1/65);咽部生殖支原体、穿通支原体和梨支原体的检出阳性率分别为 26.2%(17/65)、15.4%(10/65)和 1.5%(1/65);生殖道和咽部同时检出 Mg 者占10.8%(7/65);生殖道和咽部同时检出穿通支原体者占 4.6%(3/65);未检出发酵支原体感染者。结论在 NGU 和 MPC 患者中,生殖支原体和穿通支原体感染常见;生殖支原体和穿通支原体可能通过生殖器 - 生殖器或口 - 生殖器性接触而传播,并引起尿道炎和宫颈炎。

关 键 词：AIDS-associated mycoplasmas non-gono-coccal urethritis mucopurulent cervicitis 

分 类 号：R512.91[医药卫生—内科学]