围手术期联合应用红霉素在预防术后肠粘连的临床研究  

Clinical research about combined application of erythromycin in the prevention of postoperative adhesive ileus during perioperation

作　　者：张周义 刘华仁[1] 徐财文 杨云江[1] 张长河[1] 

机构地区：[1]广东省东莞市长安医院,东莞523843

出　　处：《岭南现代临床外科》2004年第2期103-104,共2页Lingnan Modern Clinics in Surgery

摘　　要：目的探讨围手术期联合应用红霉素对肠粘连及肠梗阻的预防作用。方法113例腹部手术患者随机分为实验组、对照组,分别记录与腹腔粘连相关的情况,随访30个月,观察粘连肠梗阻发生率。结果实验组粘连性肠梗阻发生率明显低于对照组(P<0.05),且患者用红霉素等药物未发生明显副反应。结论围手术期应用红霉素等药物及其他治疗措施可防止手术后肠梗阻及粘连性肠梗阻发生,效果肯定且安全。Objective To investigate the effects of combined application of erythromycin in the prevention of postoperative adhesive ileus during perioperation. Methods 113 patients received abdominal operation were randomly divided into experimental group and control group, and correlated with status of peritoneal adhesion was recorded. Follow up time was 30 months and incidence of adhesive ileus was observated. Results In the incidence of adhesive ileus, the experimental group was obviously lower than that control group (P< 0.05).No obvious side reactions were found in patients combined with erythromycin. Conclusion Using erythromycin etc drugs and other therapeutic measure can prevent postoperative adhesive ileus during perioperation. It's effect is a affirmed and safe.

关 键 词：围手术期 红霉素 肠粘连 肠梗阻 预防 腹部外科手术 

分 类 号：R619[医药卫生—外科学]