长疗程倍他乐克治疗对慢性心力衰竭患者左心室重塑和功能的影响  

Effect of betaloc on left ventricular remodeling and cardiac function in chronic congestive heart failure

作　　者：胡景云[1] 赵永祥[2] 胡冬煦[3] 杨进福[3] 朱利军[4] 阳国平[4] 

机构地区：[1]中南大学湘雅医学院益阳临床学院心内科,湖南益阳413000 [2]中南大学湘雅三医院心胸外科,湖南长沙410013 [3]中南大学湘雅二医院心胸外科,湖南长沙410011 [4]中南大学湘雅移植医学研究院,湖南长沙410013

出　　处：《中国医学工程》2004年第3期77-78,共2页China Medical Engineering

基　　金：国家211工程部省共建重点学科重大项目基金No[1998]6号

摘　　要：目的探讨倍他乐克治疗对慢性充血性心力衰竭患者左心室重塑和功能的影响。方法61例慢性充血性心力衰竭患者随机分为治疗组和对照组,对照组常规给予抗心衰治疗。治疗组加服倍他乐克,治疗前和治疗6个月后观察左心室结构和功能指标的变化。结果治疗组左心室结构和功能均有明显改善,与对照组相比,左心室射血分数和心输出量明显增加(P<0.05)。结论在强心、利尿。Objective: To investigate the effects of Betaloc on the left ventricular remodeling and cardiac function in chronic congestive heart failure. Methods: 61 patients on a baseline therapy including digitals, diuretics and ACEI were divided randomly into Betaloc group and control group for 6 months follow up period. The left ventricular function was measured by echocardiography before and after 6 months admission. Results: NYHA class, left ventricular ejection fraction and remodeling were improved in Betaloc group than that in control group (P<0.05). Conclusion: Based on the medication of digitalis, diuretics and ACEI, Betaloc can be improved left ventricular function and remodeling in chronic congestive heart failure.

关 键 词：慢性充血性心力衰竭 倍他乐克 左心室重塑 心脏功能 药理作用 临床疗效 

分 类 号：R541.61[医药卫生—心血管疾病]