Bi(OTf)_3-LiClO_4催化异丁基苯乙酰化反应  

Acylation of Isobutylbenzene over Bi(OTf)_3 in Nitromethane

作　　者：刘文明[1] 聂进[1] 周三一[1] 张正波[1] 

机构地区：[1]华中科技大学化学系,武汉430074

出　　处：《应用化学》2004年第8期862-864,共3页Chinese Journal of Applied Chemistry

摘　　要：The acylation of isobutylbenzene by using catalytic amount of Bi(OTf) 3 has been investigated as function of reaction time, reaction temperature, catalyst dosage and acetyl chloride. It was found that the catalytic activity of Bi(OTf) 3 could be greatly enhanced in the presence of LiClO 4 in nitromethane. Under the optimum condition: Bi(OTf) 3 20%, 4 mol/L LiClO 4-CH 3NO 2, 8 h and 100 ℃, the yield of 4-isobutylacetophenone was up to 90%.The acylation of isobutylbenzene by using catalytic amount of Bi(OTf) 3 has been investigated as function of reaction time, reaction temperature, catalyst dosage and acetyl chloride. It was found that the catalytic activity of Bi(OTf) 3 could be greatly enhanced in the presence of LiClO 4 in nitromethane. Under the optimum condition: Bi(OTf) 3 20%, 4 mol/L LiClO 4-CH 3NO 2, 8 h and 100 ℃, the yield of 4-isobutylacetophenone was up to 90%.

关 键 词：异丁基苯 乙酰化 三(三氟甲基磺酸)铋 高氯酸锂 

分 类 号：O621.2[理学—有机化学]