基因芯片及其在性传播疾病病原体研究中的应用  

Gene chips and their applications to the studies on the pathogens responsible for the sex ual ly trans mit ted dis eases

作　　者：石岗[1,2] 王升启[1] 

机构地区：[1]军事医学科学院放射医学研究所 [2]北京市农林科学院畜牧兽医研究所,北京100089

出　　处：《生物技术通讯》2004年第4期392-395,共4页Letters in Biotechnology

摘　　要：基因芯片是近年发展起来的一种高通量的核酸分析技术,已成为“后基因组时代”的重要分析工具之一。本文简述了基因芯片的概念、分类及特点,并对基因芯片技术在性传播疾病病原体淋球菌、沙眼衣原体、解脲脲原体和人乳头瘤病毒研究中的应用作了综述。Gene chip,which has been developed recently,is a high-throughput technology for the nucleic acid analysis and has become one of the most powerful tools in the″Post-Genome Era″.In this paper,the concept of the gene chip and its classifications and advantages are introduced briefly and its applications to the studies on the pathogens responsi-ble for the sexually transmitted diseases such as Neisseria gonorrhoeae,Chlamydia trachomatis,Ureaplasma urealyticum and human papillomavirus are reviewed.

关 键 词：基因芯片 性传播疾病 病原体 核酸分析技术 

分 类 号：R37[医药卫生—病原生物学] Q503[医药卫生—基础医学]