中西医结合治疗继发性磺脲类失效2型糖尿病98例  

Combined Chinese and Western Medicine for 98 Cases of Secondary Type 2 Diabetes Mellitus Irresponsive to Sulfaurea Drugs

作　　者：张英来[1] 张军[1] 谢富明[1] 

机构地区：[1]河北唐山市中医院,河北唐山063000

出　　处：《上海中医药杂志》2004年第7期18-19,共2页Shanghai Journal of Traditional Chinese Medicine

摘　　要：观察益气养阴活血方药治疗继发性磺脲类失效的 2型糖尿病 (DM )患者的疗效 ,及对空腹血糖 (FBG)、糖化血红蛋白 (HbAlc)、C肽 (C P)水平的影响。将 98例继发性磺脲类降糖药物失效的 2型DM气阴两虚兼血瘀患者 ,随机分为单纯应用胰岛素对照组及中药加胰岛素治疗组 ,疗程 12周。结果 :两组治疗后FBG、HbAlc均较治疗前明显降低 (P <0 0 1) ,治疗组降低更明显 ,与对照组比较有显著性差异 (P <0 0 5 ) ;治疗组有效胰岛素剂量显著低于对照组 (P <0 0 5 )。提示益气养阴活血方药对继发性磺脲类失效的 2型DM气阴两虚兼血瘀患者 ,有协同胰岛素降糖作用 。To observe the clinical efficacy of qi-yin-enriching and blood-activating herbs in the treatment of type 2 diabetes mellitus (DM) irresponsive to sulfaurea drugs, FBG, HbALc and C-P were measured. Ninety-eight subjects were randomized into two groups: control group in which simple insulin was given and treatment group in which both insulin and Chinese herbs were given, with a course of 12 weeks. Results: After treatment, FBG and HbAlc fell obviously in both groups (P<0.01), with more remarkable falling in treatment group than in control group (P<0.05); the dosage of insulin used was lower in treatment group than in control group (P<0.05). It is indicated that these herbs are effective for DM and can reduce the use of insulin.

关 键 词：2型糖尿病 继发磺脲类降糖药失效 益气养阴活血 

分 类 号：R587.1[医药卫生—内分泌]