深绿山龙眼中二个新的植物脑苷的结构鉴定  

Structure identification of two new cerebrosides from Helicia nilagirica Beed.

作　　者：吴彤[1] 孔德云[1] 李惠庭[1] 

机构地区：[1]上海医药工业研究院,上海200040

出　　处：《药学学报》2004年第7期525-527,共3页Acta Pharmaceutica Sinica

摘　　要：目的　研究深绿山龙眼Helicianilagirica的化学成分。方法　应用硅胶柱色谱法对深绿山龙眼叶子的化学成分进行分离 ,根据理化常数测定和光谱分析鉴定化合物的结构。结果　得到 2个植物脑苷化合物 :HeliciacerebrosidesA(1)和B(2 )。确定了 1的结构 ,并初步推定 2的结构。结论　化合物 1和Aim To study the bioactive components from Helicia nilagirica. Methods Compounds were separated with a combination of multi-chromatography. Their chemical structures were determined on the basis of spectral analysis and chemical evidence. Results Two compounds were isolated from the leaves of Helicia nilagirica. Compound 1 was elucidated as 1-O-β-D-glucopyranosyl-(2S,3S,4R,8Z)-2-[(2′R)-2′-hydroxylignocenoyl-amino]-8-octadecene-1,3,4-triol. Compound 2 was an analogue of 1. Conclusion The two compounds are new cerebrosides.

关 键 词：深绿山龙眼 植物脑苷 Helicia CEREBROSIDE A Helicia CEREBROSIDE B 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]