Nd:YAP激光照射犬离体子宫壁生物效应的实验研究  

Experimental Study of Biological Effects on Canine Uterus by Nd:YAP Laser

作　　者：包晓青[1] 朱菁[1] 袁霞雯[1] 张慧国[1] 张美珏[1] 秦梅香[1] 施虹敏[1] 

机构地区：[1]上海第二医科大学附属仁济医院上海市激光医学研究中心,上海200001

出　　处：《应用激光》2004年第3期184-188,共5页Applied Laser

摘　　要：目的 :研究Nd :YAP激光不同剂量的组合对犬离体子宫壁照射后生物效应的差异。方法 :以犬作为实验对象 ,以不同功率、不同照射时间照射离体子宫壁 ,通过肉眼、光镜、电镜观察不同激光参数的生物学作用。结果 :Nd :YAP激光光斑直径 3mm ,作用于厚度 6mm的离体子宫壁 ,以热凝固效应为主 ,也有一定的消融作用。全层凝固变性的剂量为 30w、2s ;2 0w、4s;10w、5s。结论 :光斑直径 3mm ,作厚度 6mm的子宫壁凝固、消融时 ,以功率 30w、2s ;2 0w、4s ;10w、5s以下的剂量较为安全 ,可减少穿孔的机率。Nd :YAP激光的组织消融、热凝固作用与平均功率、照射时间成正相关。Objective: To observe the difference of biological effects on canine by Nd:YAP laser with different power and irradiation time. Method: The canine uterus were irradiated with different power and different irradiation time. We observed the effects of ablation and thermal coagulation of different laser settings. We evaluated the damage scale with naked eyes、microscope and electroscope. Result: The thermal coagulation is primary and ablation is secondary. The dose of perforation is 30w、2s;20w、4s and 10w、5s. The diameter offacula is 3mm,Conclusion: The thermal coagulation is primary and ablation is secondary of Nd:YAP laser on canine uterus. Safety dose is less than 30w、2s;20w、4s or 10w、5s. The diameter offacula is 3mm,The ablation and thermal coagulation effect of Nd:YAP laser on canine uterus is relevant to mean power and irradiation time

关 键 词：ND:YAP激光 生物效应 激光照射 离体子宫壁 热凝固 

分 类 号：R711.74[医药卫生—妇产科学]