小儿女阴感染的临床特征及防治研究  

Researching the clinical manifestation and prevention on the infection in female infant pudenda

作　　者：鞠玉蕊[1] 袁久彤[1] 胡桂芝[1] 尹棋[1] 赵艳玲[1] 

机构地区：[1]长春市儿童医院,吉林长春130061

出　　处：《吉林医学》2004年第6期37-39,共3页Jilin Medical Journal

摘　　要：目的为探讨小儿女阴感染的临床特征及防治手段。方法应用PCR-DNA对小儿女阴及尿道口分泌物进行解脲支原体(UU)、衣原体(Ct)及淋球进行检测,同时观察三种病原体感染的临床表现,找出临床特征,以利基层医疗单位诊断治疗。结果UU、Ct主要临床特征为尿道口分泌物增多,无色,外阴痒感,但无阴道炎表现。淋菌感染者分泌物黄色或脓性,有异味或臭味,小阴唇及阴道黏膜充血,临床特征与PCR-DNA检测UU、Ct及淋菌阳性符合率分别为98.18%97.83%及100%。母UU、Ct及淋菌女阴感染者,其女儿PCR-DNA检出率分别为66.67%83.33%及45.00%。AR%值分别为97.37%98.15%及74.81%。小儿有公共浴池洗浴史者,女阴分泌物UU-RCR-DNA阳性为42.86%、Ct为43.33%、淋菌为66.67%,与无公共浴池洗浴史者UU、Ct、淋菌等PCR-DNA检测阳性率间P<0.05。AR%分别为85.29%98.15%及18.70%。经阿奇毒素治疗10d阴转率,UU为72.50%、Ct为64.71%、淋菌为90.00%。6个月阴转率UU为92.50%、Ct为97.14%、淋菌为90.00%。结论UU、Ct及淋菌PCR检测阳性者与临床特征基本一致,P>0.05。在不具备先进检测设备的基层医疗单位可根据临床特征诊断、筛选、进行治疗,据AR%值推算,如除去母患女阴炎因素,UU、Ct及淋菌女婴女阴炎发病率可分别在原有病率基础上,再下降97.37%98.15%及94.Objective To research the clinical manifestation and prevention on the infection in female infant pudenda. Method Testing urine mycoplasma(UU),chlamydia(Ct)and lymphocyte in secretion from female infant vagina and urethra with PCR-DNA. To find out the clinical manifestation of these pathogens for clinical diagnosis. Results The clinical manifestation of UU and CtSecretion from urethra increases. Secretion has no colour.Pudenda itch,not vaginitis.But lymphocyte infectionsecretion is yellow,like pus,smelly.Nympha and vagina mucous membrane congest.As compared with clinical manifestation,the positive percentage(rate)of UU,Ct and lymphocyte PCR-DNA test are 98.18%,97.83% and 100%?If the mother has UU,Ct and lymphocyte infection in pudenda,the daughter's PCR-DNA test infection percentage(rate) are 66.67%,83.33%,45% and AR% are 97.37%,98.15%,74.81%?The secretion from the female infant who go to the public bathroom was tested in PCR-DNA and positive percentage are UU 42.86%,Ct 43.33%,lymphocyte 66.67%,The secretion from the one who not go to public bath was tested,positive ratio show P<0.05. And AR% are 85.29%,98.15%,18.70%?We treated patient with Azithromycin,the test turn to negative in ten days,the percentage are UU 72.50%?Ct 64.71%?lymphocyte 90.00% and in six month the percentage are UU 92.50%,Ct 97.14%?lymphocyte 90.00%?Conclusion UU,Ct,and lymphocyte PCR-DNA test positive result fit to the clinical manifestation basically,P>0.05. If a hospital has no advanced test equipment,they can diagnose and treat according to the clinical manifestation.Calculating through AR%,mother vaginitis apart,female infant pudenda disease down to UU97.37%,Ct98.15%,lymphocyte 94.48%?Public bath apart, above disease down to UU 85.29%,Ct 98.15%,lymphocyte 84.00%?Azithromycin is effective on preventing and curing UU,Ct,lymphocyte infection.

关 键 词：解脲支原体 衣原体 淋菌 临床特征 小儿女阴感染防治 

分 类 号：R711.3[医药卫生—妇产科学]