肺炎链球菌所致下呼吸道感染的耐药性分析  

Analysis of the drug resistance of Streptococcus pneumoniae induced lower respiratory infection

作　　者：刘克强[1] 司进[1] 张菊英[1] 葛庚芝[1] 

机构地区：[1]天津医科大学第二医院呼吸科,天津300211

出　　处：《中国中西医结合急救杂志》2004年第4期242-244,共3页Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care

摘　　要：目的 :调查近期天津市肺炎链球菌下呼吸道感染的耐药情况。方法 :对天津市 10所医院 2 0 0 0—2 0 0 2年收治的 6 1例肺炎链球菌所致下呼吸道感染成人患者的细菌培养结果进行回顾性分析 ,药敏试验采用琼脂纸片扩散法。结果 :药敏结果显示 ,6 1株肺炎链球菌对青霉素的耐药率为 13.1% ,头孢噻肟没有耐药菌 ,其他 β 内酰胺类抗生素的耐药率为 2 .9%～ 10 .0 % ,红霉素的耐药率为 4 7.1% ,左氧氟沙星耐药率为 17.8% ,万古霉素没有发现耐药菌。结论 :青霉素仍可作为肺炎链球菌所致下呼吸道感染最有效的抗生素 ,喹诺酮类抗生素耐药率升高应引起高度重视。Objective: To investigate drug resistant of lower respiratory infection caused by (Streptococcus) pneumoniae in Tianjin. Methods: The antibiotic susceptibility studies of 61 cases from (respiration) (department) of 10 hospitals in Tianjin and during 2000-2002 were reviewed. KirbyBauer agar (diffusion) (method) was used. Results: The antibiotic susceptibility studies showed that the resistance rates of (Streptococcus) pneumoniae to penicillin were 13.1%. All of the strains were suscepococcus to cefotaxime. The resistance rates of Streptococcus paeumoniae to the other betalactams were 2.9%10.0%, to erythromycin were (higher) (47.1%), to levofloxacin were 17.8%. All of the strains were suscepococcus to vancomycin. (Conclusion): The rate of resistance to penicillin has remained low and it's an effective drug on treating (respiratory) (infection) caused by Streptococcus pneumoniae. It should pay much attention to that (fluoroquinolones) has (been) (increased) with the extensive use of antimicrobial agents.

关 键 词：下呼吸道感染 肺炎链球菌 耐药性 

分 类 号：R56[医药卫生—呼吸系统]