黄龙肝脂消颗粒质量标准的实验研究  

Study on quality standard for Huanglongganzhixiao Granule

作　　者：秦华珍[1] 邓家刚[1] 陈勇[1] 谢臻[1] 李烟生[1] 

机构地区：[1]广西中医学院药学院,广西南宁530001

出　　处：《中成药》2004年第7期535-538,共4页Chinese Traditional Patent Medicine

基　　金：广西科技厅"科技三项"科技攻关项目资助 (桂科攻 0 2 3 5 0 2 3 -7)

摘　　要：目的 :建立黄龙肝脂消颗粒 (龙血竭、黄芪、淫羊藿 ,等 )的质量标准。方法 :采用TLC法对处方中的黄芪、龙血竭、淫羊藿进行定性鉴别 ,用HPLC测定制剂中龙血素B的含量。结果 :在TLC鉴别中均能检出黄芪、龙血竭、淫羊藿 ,龙血素B进样量在 0 .0 32～ 0 .0 96 μg范围内有良好的线形关系 ,r=0 .9997(n =5 ) ,平均回收率 1 0 0 .1 % ,RSD =3.33% (n =6 )。结论 :该法简便、准确、专属性强 。AIM: To establish the quality standard for Huanglongganzhixiao Granule(Resina Draconis, Radix Astragali, Herba Epimedii, etc.). METHODS: Radix Astragali, Resina Draconis, Herba Epimedii in Huanglongganzhixiao Granule were identified by TLC. The content of loureirin B in this Granule was determined by HPLC. RESULTS: Radix Astragali, Resina Draconis, Herba Epimedii could be identified by TLC. Loureirin B showed a good linear relationship at a range of 0.032～0.096μg, r =0.9997( n =5). The average recovery was 100.1% and RSD was 3.33%. CONCLUSION: The method is simple, accurate and with strong specificity and can be used for the quality control of Huanglongganzhixiao Granule.

关 键 词：黄龙肝脂消颗粒 TLC 龙血素B HPLC 

分 类 号：R927.2[医药卫生—药学]