染料中间体溴代硝基苯胺的结构鉴定和HPLC分析  

Identification of the Structure and HPLC Analysis of Bromonitroaniline and Its By-product

作　　者：周心如[1] 沈力阳[1] 杨榕 

机构地区：[1]北京化工学院应用化学系

出　　处：《分析测试学报》1993年第2期18-21,共4页Journal of Instrumental Analysis

摘　　要：本文提出测定4-溴-2-硝基苯胺(1)及其副反应产物的高效液相色谱(HPLC)分析方法。用紫外光谱、红外光谱、核磁共振氢谱鉴定(1)及副产物4,6-二溴-2-硝基苯胺(2)的结构。高效液相色谱采用的色谱柱为CLC-Ph柱(φ6×150mm),流动相为甲醇-水(70:30),测定的变异系数对于(1)和(2)分别为0.45%和1.07%,回收率分别为99.5%和99.7%。The Structures of 4-bromo-2-nitroaniline and its by-Product, 4,6-dibromo-2-nitroaniline,are identified by means of UV, IR, and NMR ~1H. and then their content are determined byHPLC using a column of CLC-Ph(φ6x150 mm)and a mobile phase of a mixture of methanoland water in volume ratio 70:30. The coeffecient of variation and recoveries for the dye in-termediate and its by-product are respectively 0.45% and 1.07% as well as 99.5% and 99.7%

关 键 词：HPLC 染料中间体 溴代硝基苯胺 

分 类 号：TQ612[化学工程—精细化工]