盐酸噻氯匹定单用与联用低分子量肝素对不稳定型心绞痛治疗作用比较  

Contrast of the effect of ticopidine and ticopidine adding low molecular weight heparin on untable angina pectoric(UAP)

作　　者：张远东[1] 杨红[1] 

机构地区：[1]山东省新泰市人民医院心内科,271200

出　　处：《基层医学论坛》2004年第7期594-595,共2页The Medical Forum

摘　　要：目的观察单用盐酸噻氯匹定(辰欣)和联用低分子量肝素(法安明)治疗不稳定型心绞痛(UAP)的临床疗效。方法将86例 UAP 患者随机分为对照组(盐酸噻氯匹定)及治疗组(盐酸噻氯匹啶+法安明),疗程为1周。结果 1周后总有效率:治疗组为88.37%,对照组为67.44%(P<0.05);观察4用治疗组无1例发生急性心肌梗死,对照组发生3例(9.38%);治疗组未发生明显不良反应。结论在常规治疗基础上加用低分子量肝素能更有效地控制心绞痛发作,减少心肌梗死发生率。Objective To observe the clinical effect of treatment on untable angina pectoric(UAP)with single ticopidine and ticlopidine adding low molecular weight heparin(LMWH).Methods 86 UAP patients were divided into two groups,control group(toclopidine)and treated group(ticlopidone and low molecular weight heparin).The course of treatment had lasted 4 weeks.Results The total efficient rate was 88.37% in the treat- ed group,while in the control group was 67.44% in 4 weeks(P<0.05).And no cases had acute myocardial in- farction in the trdated group but 3 cases in the control group(9.38%).No obviously complication was found in the treated group.Conclusion The treatment with LMWH basing on routine treatment can effectively control the outbreak of angina pectoris and decrease the incidence of acute myocardial infarction.

关 键 词：盐酸噻氯匹定 低分子量肝素 不稳定心绞痛 治疗 

分 类 号：R541.4[医药卫生—心血管疾病]