多维气相色谱用于手性对映体的分离  

Enantiomer Separation by Multidimensional Gas Chromatography With a Chiral Main Column

作　　者：王秀红[1] 贾崇荣[1] 万宏[1] 欧庆瑜[1] 

机构地区：[1]中国科学院兰州化学物理研究所,兰州730000

出　　处：《分析化学》1993年第5期495-499,共5页Chinese Journal of Analytical Chemistry

基　　金：国家自然科学基金

摘　　要：本文利用多维气相色谱方法(MDGC)。手性柱作为主分离柱,分析了人工合成样品中的手性组分α-苯乙胺及α-溴丁酸甲酯。作为实际应用,对大茴香精油、小茴香精油及玫瑰精油中的旋光性萜烯-柠檬烯用多维气相色谱方法进行了直接分离,并测定了三种精油中柠檬烯对映体的过剩量值(比值)。The enantiomer separation of α-phenethylamine and α-bromomethylbutyrate in artificial mixtures was effected by using multidimensional gas chromatography(MDGC) with a chiral main column which was chirasil-val or heptakis (2, 3, 6-tri-O-pentyl)-β-cyclodextrin. To demonstrate the potential of MDGC in the analysis of chiral components presented in complex samples, direct separation of R(+),S(-)-limonene in three essential oils by using perpentyl-β-cyclodextrin as the second column was achieved and the ratio of R (+)-limonene to S(-)-limonene was calculated. It showed that MDGC with a chiral main column was a powerful fool in the differentiation of chiral components.

关 键 词：多维气相色谱 对映体 分离 

分 类 号：O657.71[理学—分析化学]