治疗方案与慢性肾功能衰竭患者认知功能的关系  

Relation between medical treatments and cognitive function in patients with chronic renal failure

作　　者：岳红红[1] 王汉民[1] 苗丹民[2] 汪涌[3] 肖力军[2] 鲍炜[4] 

机构地区：[1]解放军第四军医大学西京医院肾脏病学内科,陕西省西安市710032 [2]解放军第四军医大学航空航天医学系心理学教研室,陕西省西安市710032 [3]解放军第四军医大学西京医院泌尿外科,陕西省西安市710032 [4]解放军第四军医大学生化教研室,陕西省西安市710032

出　　处：《中国临床康复》2004年第21期4152-4153,共2页Chinese Journal of Clinical Rehabilitation

摘　　要：目的:探讨不同治疗方法对慢性肾功能衰竭患者的认知功能的影响。方法:将慢性肾功能衰竭患者40例随机分为4组,每组10例。分别予以血液透析+促红素、促红素、血液透析及内科保守等治疗3个月。每组患者治疗前后均接受字母划消测试验、连续相加测验。结果:血液透析+促红素治疗组、促红素治疗组和血液透析治疗组的字母划消测试验、连续相加测验成绩治疗前后差异均有显著性意义(P均<0.01);内科保守治疗组治疗前后差异无显著性意义(P>0.05)。结论:血液透析+促红素治疗能较好的改善慢性肾功能衰竭患者的认知功能;促红素或血液透析治疗,也可在一定程度上改善患者的认知功能;内科保守治疗对患者的认知功能的改善效果不明显。AIM:To explore the effects of different treatments on cognitive function in patients chronic renal failure(CRF). METHODS:Forty patients with CRF were randomly divided into 4 groups of 10 patients each, and they were treated with hemodialysis(HD)?erythropoietin(Epo),Epo,HD and conservative internal medical treatment respectively for 3 months.All the patients received letter cancel test(LCT) and continuous adding test before and after treatments. RESULTS:The scores of LCT and continuous adding test after treatment were significantly different from those before treatment in the HD?Epo,Epo and HD groups(P< 0.01);while there was no significant difference in the conservative internal medical treatment group(P >0.05).CONCLUSION:HD?Epo can improve the cognitive function of patients with CRF greatly; and HD or Epo can improve it to some extent,while conservative internal medical treatment has no obviously effect.

关 键 词：慢性肾功能衰竭 认知功能 血液透析 内科保守治疗 促红素 

分 类 号：R692.5[医药卫生—泌尿科学]