床旁B型利钠肽测定在急性呼吸困难鉴别诊断中的应用  

APPLIED RESEARCH OF BED-SIDE B TYPE NATRIURETIC PEPTIDE ASSAYS IN DIFFERENTIATING ACUTE DYSPNEA

作　　者：王如兴[1] 李肖蓉[1] 邵力正[1] 羊镇宇[1] 肖春晖[1] 王强[1] 杨光敏[1] 

机构地区：[1]江苏省无锡市第一人民医院心内科,214002

出　　处：《中国心血管病研究》2004年第8期604-606,共3页Chinese Journal of Cardiovascular Research

摘　　要：目的探讨床旁B型利钠肽(BNP)测定对急性呼吸困难鉴别诊断的敏感性、特异性和准确性。方法采用美国博适-Triage干式快速定量心力衰竭/心肌梗死诊断仪对351例心源性和非心源性呼吸困难患者床旁BNP测定。结果按纽约心脏病协会(NYHA)不同心功能分级患者BNP水平不同;BNP水平<60pg/ml患者基本可诊断为非心源性呼吸困难;BNP水平>100pg/ml但<500pg/ml患者需考虑可能为心源性呼吸困难;>500pg/ml患者基本可诊断为心源性呼吸困难。结论BNP水平高低是鉴别心源性和非心源性呼吸困难可靠的指标。Objective To investigate sensitivity,specialty and accuracy of B type natriuretic peptide (BNP) assays in differentiating cardiac and non-cardiac dyspnea. Methods BNP levels of 351 patients with cardiac or non-cardiac dyspnea were measured by Triage CHF/AMI analyzer made by American Biosite company. Results BNP levels were different in different cardiac function patients according to NYHA;When BNP level is less than 60pg/ml,non-cardiac dyspnea can be diagnosed;when BNP level is between 100pg/ml and 500pg/ml,cardiac dyspnea should be considered;when BNP level is more than 500pg/ml,cardiac dyspnea can be diagnosed in general condition. Conclusion BNP level is an effective way to identify cardiac and non-cardiac dyspnea.

关 键 词：B型利钠肽 鉴别诊断 心源性呼吸困难 非心源性呼吸困难 

分 类 号：R56[医药卫生—呼吸系统]