电针对戊四唑点燃型癫痫大鼠脑电图的影响  

Effect of Electroacupuncture on the Electroencephalographin Rats with Pentylenetetrazol-induced Seizure

作　　者：昂文平[1] 杨帆[1] 王频[1] 徐国龙[1] 章复清[1] 刘向国[1] 郭宝田 

机构地区：[1]安徽中医学院,安徽合肥230038 [2]安徽省阜阳卫生学校

出　　处：《安徽中医学院学报》2004年第4期20-22,共3页Journal of Anhui Traditional Chinese Medical College

基　　金：安徽省教育厅自然科学研究基金项目 (1 999JL1 39) ;安徽省教育厅青年教师科研基金项目 (2 0 0 0QL1 4 8)

摘　　要：目的 :探讨戊四唑 (PTZ)致痫大鼠脑电图的变化及电针对其影响。方法 :成年SD大鼠30只随机分为正常对照组、PTZ致痫组和电针组 ,每组 1 0只。采用多导生理记录仪记录大鼠脑电变化情况。结果 :电针组大鼠脑电痫波潜伏期较PTZ致痫组延长 (P <0 .0 5 ) ;痫波持续时间明显缩短 (P <0 .0 1 ) ;发作频率明显减少 (P <0 .0 1 )。结论 :电针可明显抑制PTZ诱导的大鼠癫痫发作。Objective:To observe the changes of electroencephalograph(EEG) in rats with pentylenetetrazol(PTZ) induced seizure and to explore the effect of electroacupuncture(EA). Method: Thirty SD rats wererandomly divided into three groups (10 rats in each group): control group, epilepsy model group and EA group. EEG of rats was recorded with multipurpose polygraph.Result: In EA group,the incubation period of epileptic wave was prolonged(P<0.05);the duration and frequencies of epileptic wave were all obviously reduced(P<0.01). Conclusion: EA can significantly inhibit the PTZ induced seizures in rats.

关 键 词：癫痫 电针 脑电图 

分 类 号：R245.31[医药卫生—针灸推拿学]