经皮睾丸精子抽吸术的临床应用  

The clinical application of percutaneous testicular sperm Aspiration

作　　者：陈国武[1] 曹翔[1] 汤晓峰[1] 曹英[1] 董曦[1] 韩金兰[1] 严敬明[1] 

机构地区：[1]上海集爱遗传与不育诊疗中心,上海200011

出　　处：《中国男科学杂志》2004年第4期25-27,共3页Chinese Journal of Andrology

摘　　要：目的探讨经皮睾丸精子抽吸术在临床上的应用.方法135例患者分为3组:梗阻性无精子症组(OA组)71例,先天性无精子症组(CC组)23例,原发性无精子症组(IA组)41例,所有患者均做经皮睾丸精子抽吸术及单精子注射术.结果通过经皮睾丸精子抽吸术(PTAS)获得精子的平均密度为73.5±42.59/μ1,平均活动率为(1.5±1.17)%(范围1%～5%),共1263个成熟卵子行ICSI,获得849个正常胚胎(正常受精率为67.2%).在OA组中,71例患者行79周期,32例怀孕.在CC组中,23例患者行28周期,9例怀孕.在IA组中,41例患者行41周期,8例怀孕.结论PTSA合ICSI是一种治疗梗阻性无精子症的有效手段,且梗阻性无精子症患者的妊娠率高于特发性无精子症患者.Objective To analysis the clinical application of percutaneous testicular sperm aspiration (PTSA).Methods All the cases were divided into 3 group, one is obstructive azoospermia (OA group, 71 cases), second iscongenital causes (CC group, 23 cases), and the third is idiopathic azoospermia (IA group, 41 cases). All of themunderwent embryo transfer using ICSI with testicular sperm by PTSA. Results As to testicular sperm, the concen-tration is 73.542.59/μl, the motility is (1.51.17)% (range is 1%~5%) the grade of motility is 1. 1263 mature eggswere done with ICSI. After ICSI, 849 normal embryos (normal fertilization rate is 67.2%) were got. In Obstructiveazoospermia group, 71 cases did 79 cycles and 32 cases got pregnancy (pregnancy rate is 40.5%). In congenital causesgroup, 23 cases did 28 cycles and 9 cases got pregnancy (pregnancy rate is 32.1%). In idiopathic azoospermia group,41 cases did 41 cycles and 8 cases got pregnancy (pregnancy rate is 19.5%). Conclusion ICSI with PTSA is a kindof effective method to treat the man with azoospermia. Using this method, the pregnancy rate of obstructive azoosper-mia is higher than that of idiopathic azoospermia.

关 键 词：经皮睾丸精子抽吸术 单精子卵细胞浆内注射术 精子 

分 类 号：R321-33[医药卫生—人体解剖和组织胚胎学]