自身免疫性甲状腺炎患者降钙素储备功能的测定  

Determination of caldtonin reserve function in patients with autoimmune thyoiditis

作　　者：李子玲[1] 张士明[2] 黎云燕[2] 王艳萍[2] 马伯海[3] 张煜[3] 

机构地区：[1]内蒙古医学院第三附属医院内分泌科,包头014010 [2]天津医科大学第二医院 [3]天津医科大学津城放免中心

出　　处：《中国骨质疏松杂志》2004年第2期234-235,134,共3页Chinese Journal of Osteoporosis

摘　　要：目的 为探讨AITD患者降钙素储备功能。方法 采用钙负荷-降钙素兴奋试验观察33例AITD患者CT基础值及其储备功能的改变,并与25例健康女性进行比较。AITD患者以具有典型的甲状腺机能减退的临床症状,甲状腺肿大,化验检查证实血清总T3、总T4降低和(或)FT3、FT4降低并伴有TSH明显增高,甲状腺球蛋白抗体(TGAb)和甲状腺微粒体抗体(TMAb)阳性为诊断标准。血清钙采用电极法测定,CT采用放免法测定,所有资料均输入微机,用SPSS软件包进行统计学处理。结果AITD患者CT基础值及其储备功能均低于对照组。结论 AITD患者在甲状腺滤泡细胞受损的同时,其C细胞也同时受到损伤,使CT分泌及储备功能减少。Objective To study the calcitonin reserve function in patients with autoimmune thyroiditis AITD, calcium lading calcitonin stimulated test was conducted in 33 patients and 25 healthy women as controls. We compared the results between the two groups. The results showed that the basal calcitonin and the maximum calcitonin after calcium loading in the patients with AITD were lower than those in the normal controls. This study shows that when the follicular cells of the thyroid are damaged, the C cells are damaged also.

关 键 词：自身免疫性甲状腺炎 降钙素 储备功能 测定 甲状腺球蛋白抗体 甲状腺微粒体抗体 

分 类 号：R581.4[医药卫生—内分泌]