细胞凋亡诱导剂研究进展  

Recent Developments of Apoptosis Inducer

作　　者：沙磊[1] 赵宝祥[1] 谭伟[1] 苗俊英[2] 

机构地区：[1]山东大学化学与化工学院,济南250100 [2]山东大学生命科学学院,济南250100

出　　处：《有机化学》2004年第8期864-871,共8页Chinese Journal of Organic Chemistry

基　　金：山东省自然科学基金重点 (No .Z2 0 0 2D0 5);山东大学跨学科研究基金资助项目

摘　　要：细胞凋亡诱导剂作为癌症治疗药物日益受到重视 ,并已应用于临床研究 ,是一类非常有应用前景的药物 .综述了近年来细胞凋亡诱导剂的研究状况及进展 。The apoptosis inducers as anticancer reagents have attracted considerable attention, and now some of them have been used in clinic. They are the promising drugs toward cancer treatment. This paper reviews the recent development of apoptosis inducer with an emphasis on their structures and their structure-activity relationship.

关 键 词：细胞凋亡 诱导剂 抗癌药物 构效关系 结构类型 

分 类 号：R98[医药卫生—药品]