医用聚乳酸的合成及其管型材料性能的测定  

THE SYNTHESIS OF POLY(D,L-LACTIC ACID) FOR MEDICAL USE AND THE DETERMINATION OF SOME PROPERTIES OF ITS TUBE

作　　者：何永言[1] 夏淑贞[1] 吴蒙[1] 王海龙[2] 

机构地区：[1]同济医科大学,武汉430033 [2]华中理工大学,武汉430074

出　　处：《高分子材料科学与工程》1993年第2期24-28,共5页Polymer Materials Science & Engineering

摘　　要：本文以无毒的辛酸亚锡作催化剂,将丙交酯聚合成聚乳酸(PLA)。研究了在760～0.05mmHg范围内压力改变对PLA分子量的影响,并将PL制成内径为2mm的管型材料,经热稳定性、机械强度和降解性能等试验,结果都表明此管材可用作引导神经再生导管材料。With the nonpoisnous stannous octoate as the catalyst,the lactide was polymerized to poly(D,L-Lactic acid ) (PLA). The influences of pressure between 760-0.05mmHg on the molecular weights of poly(D,L-Lactic acid)were studied. The PLA was manufactured into the tubes with 2mm of inner diameter. All experimental results of the heat stability,mechanical strength and the degradation rate of the tube showed that the PLA tube could be used for the guide introducting nerve regeneration.

关 键 词：聚乳酸 聚合作用 神经导管 丙交酯 

分 类 号：R318.08[医药卫生—生物医学工程]