乳腺组织切片的拉曼光谱的研究  

Raman Scattering Spectra of Breast Histological Sections

作　　者：姚淑霞[1] 赵元黎[1] 张录[2] 申培红[3] 葛向红[1] 

机构地区：[1]郑州大学物理工程学院,郑州450052 [2]郑州市骨科医院,郑州450052 [3]郑州市中心医院,郑州450007

出　　处：《河南预防医学杂志》2004年第3期132-134,共3页Henan Journal of Preventive Medicine

基　　金：国家自然科学基金 (10 2 0 5 0 13)

摘　　要：目的　为医生诊断乳腺癌提供辅助手段。方法　采用激光拉曼光谱技术对乳腺组织切片进行研究。结果　细胞核上的拉曼峰较其它位置明显 ,癌变组织 86 0cm-1处的拉曼峰明显蓝移 ;16 10cm-1处的峰值与 15 2 5cm-1处的峰值比反映了病变与正常乳腺组织之间光谱的差异。结论　为激光拉曼光谱技术应用于乳腺癌的诊断提供了重要的实验依据。Purpose:To offer a assistant meas for doctor to diagnose cancer. Method:Breast histological sections are studied by laser Ramam scattering technique.Resalt:the Raman spectra peaks of cell nucleus are more prominent and the 860cm -1 band of cancer tissues shifts towards shortwave obviously. Compared the peak value of 1610cm -1 to 1525cm -1 ,it reveals that the ratios are different between normal and cancer tissues. Conclusion:These results offer valuable data for the diagnosis of breast cancer with laser Raman spectra technique.

关 键 词：拉曼光谱 乳腺组织切片 肿瘤 细胞核 

分 类 号：O433.5[机械工程—光学工程]