前庭刺激对选择注意影响的事件相关电位研究(英文)  

An Event-related Potentials Study on Selective Attention Modulated by Vestibular Stimulation *

作　　者：王林杰[1] 魏金河[2] 张丹[2] 董卫军[2] 郭建平[2] 胡耄祺[2] 

机构地区：[1]航天医学工程研究所 [2]Institute of Space Medico-Engineering,Beijing 100094

出　　处：《航天医学与医学工程》2004年第2期79-84,共6页Space Medicine & Medical Engineering

基　　金：SpecialExperimentalTechniqueProjectofChinaGeneralEquipmentDepartment( 0 110 13 0 7)

摘　　要：目的应用事件相关电位 (ERPs)技术观察线性改变前庭刺激时晚期选择注意加工的动态变化。方法 33名被试者进行了匀角速度旋转 ( 1 0°/s)和 4种水平匀角加速度旋转刺激 ,角加速度分别为0 .6°/s2 、0 .8°/s2 、1 .0°/s2 和 1 .2°/s2 。前庭刺激时被试者完成相同的等概率听觉认知任务。听觉刺激为 1 0 0 0ms随机间隔的中文数字 2到 9,任务要求被试者听到奇数 (靶信号 )快速按键 ,听到偶数 (非靶信号 )不按键。结果与对照和 4种水平匀角加速度旋转相比 ,匀速旋转时非靶信号ERPs的N2 幅值在前中央脑区显著降低 ,靶信号ERPs的N2 幅值在F4、Fz 和T4电极位置显著降低。与对照相比 ,匀速旋转时靶信号ERPs的P3潜伏期显著缩短。 4种角加速度水平 ,靶信号ERPs的P3潜伏期在 0 .8°/s2 和 1 .0°/s2刺激时较长 ,在 0 .6°/s2 和 1 .2°/s2 时较短。结论匀速旋转对晚期选择注意加工有激活作用 ,相对于匀速旋转 ,匀角加速度旋转对选择注意加工有抑制作用 ,这种抑制作用有几个层次。Objective To explore the dynamic change of the late attentional selection process under linearly varied vestibular stimuli using event-related potentials (ERPs) technique. Method Thirty-three subjects participated in the experiment. They were exposed to vestibular stimulation of constant angular velocity rotation(10°/s)and four levels of constant angular acceleration rotation, the acceleration was 0.6°/s 2, 0.8°/s 2, 1.0°/s 2, 1.2°/s 2 respectively. The same auditory go/no-go cognitive task was done during the stimulation. The task involved verbally given Chinese digit number from two to nine with 1 000 ms random interval. Subjects were asked to push the button for the odd numbers (target) and withhold to the even numbers (non-target). Result Compared with control and different level of constant angular acceleration rotation, the N 2 amplitude of non-target ERPs (NT-ERPs) decreased significantly over anterior-central scalp during 10°/s constant rotation, but the N 2 amplitude of target ERPs (T-ERPs) reduced significantly only at F 4, F z and T 4 sites. The P 3 latency of T-ERPs decreased significantly in 10°/s constant rotation in contrast with control. Under four different acceleration level, the P 3 latency of T-ERPs was relatively longer in 0.8°/s 2 and 1.0°/s 2, but shorter in 0.6°/s 2 and 1.2 °/s 2. Conclusions Constant angular velocity rotation had an activating effect on late attentional selection process. In contrast to the activation effect of constant angular velocity rotation, constant angular acceleration had an inhibition effect on the cognitive processes and this inhibition effect may have several levels.

关 键 词：事件相关电位 前庭刺激 选择注意 认知 

分 类 号：R338.8[医药卫生—人体生理学]