高血压病左心功能相关性的超声研究  

Clinic study of correlations between left atrial and left ventricular function in patients with hypertension

作　　者：钟明[1] 张薇[1] 高海青[1] 刘丹[1] 张运[1] 

机构地区：[1]山东大学齐鲁医院心内科,济南250012

出　　处：《中华超声影像学杂志》2004年第7期492-496,共5页Chinese Journal of Ultrasonography

摘　　要：目的　探讨高血压病左心房与左心室功能的相关关系。方法　对照组 2 0例 ,高血压病左心室心肌质量指数 (LVMI)正常组 3 2例 ,高血压病左心室肥厚组 16例 ,采用声学定量技术 ,测量左心房助力泵功能 (LAEF、AE)、管道功能 (CV)和储存器功能 (RV)以及左心室舒张功能。结果　左心房助力泵功能与其主动收缩前容量、RV正相关 ,与CV及左心室舒张功能负相关 ;左心房管道功能与AE、LAEF、RV和左心房主动收缩前容量显著负相关 ,与左心室舒张功能正相关 ;左心房储存器功能与左心房主动收缩前容量、LAEF正相关 ,与CV负相关 ,与左心室舒张功能指标无显著相关。结论　高血压病左心室舒张功能减退导致左心房管道功能减低、肺静脉与左心房间压差增大、左心房储存器功能增强、左心室舒张早期充盈增加 ,而管道功能与储存器功能的改变导致左心房前负荷增加和左心房收缩能力增强、左心房助力泵功能增强、左心室舒张晚期充盈增加。Objective To evaluate correlations between left atrial(LA) and left ventricular(LV) function in patients with hypertension by acoustic quantification(AQ) technique. Methods Forty-eight hypertensive patients and twenty control subjects were studied. Patients with hypertension were divided into two groups by left ventricular mass index(LVMI),normal LVMI group(32 cases) and left ventricular hypertrophy(LVH) group(16 cases). Left atrial ejection fraction(LAEF),atrial emptying volume(AE),conduit volume(CV) and reservoir volume(RV) were measured with AQ technique. Results RV and AE significantly increased in normal LVMI subgroup and LVH subgroup;CV and LAEF respectively decreased or increased in LVH subgroup. LA booster pump function positively correlated to onset atrial emptying volume and RV,negatively correlate to CV and LV diastolic function. LA conduit function positively correlated to LV diastolic function,negatively correlated to LAEF and AE,RV as well as onset atrial emptying volume. LA reservoir function positively correlated to onset atrial emptying volume and LAEF,negatively correlated to CV. There was no significant correlation between LA reservoir function and LV diastolic function. Conclusions LV diastolic dysfunction induces decreased LA conduit function and increased reservoir function,which may facilitate early diastolic filling of the left ventricle. The changes of LA conduit function and reservoir function may increase of LA preload. Enhancement of LA preload and LA systole makes increased LA booster pump function,which facilitate late diastolic filling of left ventricle.

关 键 词：高血压病 左心功能 诊断 超声心动描记术 左心室肥厚 

分 类 号：R445.1[医药卫生—影像医学与核医学]