湖北恩施地区流感局部暴发流行病原学分析  

The Pathological Analysis on an Outbreak of Influenza in Enshi Prefecture,Hubei Province

作　　者：冯玲玲[1] 霍细香[1] 叶国军[1] 肖红雨[1] 杨继先 陈朴 龚镇奎[1] 

机构地区：[1]湖北省疾病预防控制中心传染病防治研究所,武汉430079 [2]恩施自治州疾病预防控制中心 [3]宣恩县疾病预防控制中心

出　　处：《湖北预防医学杂志》2004年第3期13-15,共3页Hubei Journal of Preventive Medicine

摘　　要：目的　对恩施地区 2 0 0 3年 3月上、中旬发生的两起流感局部暴发流行进行病原学分析。方法　采集患者咽拭子进行病毒分离鉴定 ,采集急性期和恢复期双份血进行抗流感病毒 Ig G抗体测定。结果　证实湖北恩施地区出现的流感局部暴发流行是由 B型流感病毒引起的 ,分离的 B型流感病毒的抗原性与 2 0 0 1年香港分离株 (B/香港 /维多利亚 30 / 2 0 0 1)和浙江分离株 (B/浙江 / 2 / 2 0 0 1)很接近 ,而与 1999年四川分离株 (B/四川 / 397/ 1999)和 2 0 0 1年上海分离株 (B/上海 / 2 0 / 2 0 0 1)相差甚远。结论　湖北省恩施地区 2 0 0 3年 3月流感局部暴发流行是由流感病毒 B型引起的。Objective Pathogenic analysis of 2 influenza outbreaks were carried out in En-shi prefecture by March,2003. The isolated and antigenic characteristics were analyzed from the prevalence of influenza in the school of Enshi.Methods Chicken embryo inoculation was used to isolate virus from patient's swab sample, IgG antibody was detected, using acute and convedecent-phase serum pair.Results Two field strains were obtained from 10 patient swabs , influenza B was identificated, its antigenicity was similar to B/Hong Kong/Victoria/2001 and B/Zhejiang2/2001,while quite different with B/Sichuan/397/1999 and B/Shanghai/20/2001.Conclusion The pathogen of the outbreak in Enshi was the influenza B virus.

关 键 词：流行性感冒 病毒分离 血凝抑制试验 

分 类 号：R373.13[医药卫生—病原生物学]