中重度卵巢过度刺激综合征继发妊娠的妊娠结局分析  

Investigation on pregnancy outcomes of medium and sever ovarian hyperstimulation syndrome complicated pregnancy

作　　者：陈姺[1] 温远辉[1] 

机构地区：[1]广东省珠海市妇幼保健院,广东珠海519000

出　　处：《海南医学》2004年第9期39-40,42,共3页Hainan Medical Journal

摘　　要：目的　探讨应用促排卵技术致中重度卵巢过度刺激综合征继发妊娠与自然受孕妊娠结局的差异。方法　选择应用促排卵技术致中重度卵巢过度刺激综合征并继发妊娠 72例 (OHSS组 )和同期自然受孕在本院住院分娩的总体 (自然受孕组 )作比较 ,比较两组孕妇一般情况、妊娠合并症、分娩情况和新生儿预后等方面的差异。结果　⑴OHSS组孕妇平均年龄 ( 3 1.2± 3 .7)岁 ,自然受孕组孕妇为 ( 2 7.1± 3 .5 )岁 ,两组比较 ,差异有显著性 (p <0 .0 5 )。⑵OHSS组早期先兆流产 17例 ( 2 3 .6%) ,自然受孕组 3 2 5例 ( 6.9%) ,两组比较差异有极显著性 (p <0 .0 1) ;OHSS组患妊娠期糖尿病或糖耐量异常 13例 ( 18.1%) ,自然受孕组 12 0例 ( 2 .6%) ,两者比较差异有极显著性 (p <0 .0 1)。⑶OHSS组剖宫产率 62 .5 %( 4 5 72 ) ,明显高于自然受孕组 48.7%( 2 2 86 4695 )。⑷OHSS组双胎妊娠 8例 ( 11.1%) ,自然受孕双胎妊娠 79例 ,发生率 1.7%,两者比较差异有极显著性 (p <0 .0 1)。结论　OHSS组的孕妇年龄较大 ,早期先兆流产、双胎妊娠、妊娠期糖尿病及糖耐量异常的发生率高 ;分娩方式以剖宫产为主 ;Objective A study on the differences between pregnancy outcomes of spontaneous pregnancy and sever ovarian hyperstimulation syndrome (OHSS) complicated pregnancy after assisted reproductive techniques.Methods 72 cases sever OHSS complicated pregnancy after assisted reproductive techniques (OHSS group) were compared with total spontaneous pregnancy patients during the same period (control group) on general conditions, complications of pregnancy, delivery and neonatal prognosis, etc.Results (1) The mean age: OHSS group (31.2±3.7) years is higher than control group (27.1±3.5) years (p<0.05). (2)Threatened abortion happened on early pregnancy is significantly higher in OHSS group (17 cases, 23.6%) than control group (325 cases, 6.9%) (p<0.01); Gestational diabetes mellitus or gestational impaired glucose tolerance are also significantly higher in OHSS group (13 cases, 18.1%) than control group (120cases, 2.6%)(p<0.01). (3) Caesarean section rate of OHSS group ( 62.5%) is higher than control group(48.7%, 2286/4695). (4) Twin pregnancy rate is the same in OHSS group (8 cases, 11.1%) than control group(p>0.05).Conclusions OHSS group is predisposed to happened in elder age, threatened abortion happened on early pregnancy, twin pregnancy, gestational diabetes mellitus or gestational impaired glucose tolerance and high rate of caesarean section. The outcomes of prenatal fetus is the same with spontaneous pregnancy.

关 键 词：卵巢过度刺激综合征 妊娠结局 

分 类 号：R711.75[医药卫生—妇产科学]