胺碘酮治疗宽QRS型心动过速即时疗效的观察  

Clinical observation between the effects of intravenous amiodarone and propafenone in the treatment of broad QRS tachycardia

作　　者：刘明[1] 黄仕洲[1] 邓斌[1] 

机构地区：[1]广东肇庆市第一人民医院心内科,526021

出　　处：《中国基层医药》2004年第7期815-816,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的　对比胺碘酮和普罗帕酮治疗宽QRS型心动过速的疗效。方法　阵发性宽QRS型心动过速发作 2～ 38h ,随机分为胺碘酮组 ( 2 5例 )和普罗帕酮组 ( 2 4例 )。胺碘酮组静脉注射胺碘酮 15 0～ 30 0mg或改为静脉滴注 ,普罗帕酮组静脉注射普罗帕酮 70～ 2 10mg。观察其复律情况、QT间期及药物不良反应。结果　胺碘酮组对VT的复律成功率明显高于普罗帕酮组 (P <0 0 1) ,SVT复律成功率、QT间期的差异无显著意义 (P >0 0 5 ) ,复律时间普罗帕酮短于胺碘酮 ,普罗帕酮组出现 1例严重的药物不良反应。结论　宽QRS型心动过速的复律疗效胺碘酮高于普罗帕酮 。Objective To compare the effects of intravenous amiodarone and propafenone in the treatment of broad QRS tachycardi.Methods The efficacy and safety of amiodarone and propafenone were studied in 49 patients with broad QRS tachycardi 2～38 hours in duration.The amiodarone 150～750mg or propafenone 70～210mg were given intravenonsly.The cardiac rhythms,QT duration and side effects of the drugs were observed.Results The amiodarone was more effective than propafenone in converting ventricular tach cardia(P<0.01).In converting SVT and QT duration,there was no significant difference(P>0.05).1 patient using propafenone had serious side effects of the drugs.Conclusion These data demonstrate that amiodarone is more effective than propafenone in converting broad QRS tachycardi.

关 键 词：胺碘酮 治疗 宽QRS型心动过速 普罗帕酮 静脉注射 

分 类 号：R541.7[医药卫生—心血管疾病]