高血压合并左心室肥厚患者的临床表现及其与冠状动脉病变的关系  

Relationship between the characteristic of hypertension with left ventricular hypertrophy and coronary lesion

作　　者：龚艳艳[1] 孙寅光[1] 沈卫峰[1] 尹中君[2] 

机构地区：[1]上海第二医科大学附属瑞金医院心脏科 [2]山东省胸科医院心内科

出　　处：《临床内科杂志》2004年第8期517-519,共3页Journal of Clinical Internal Medicine

摘　　要：目的　探讨高血压合并左心室肥厚 (LVH)患者的临床表现及其与冠状动脉 (冠脉 )病变的关系。方法　观察 12 2例高血压伴胸痛住院患者的临床表现 ,45例伴左心室肥厚为LVH组 ,77例不伴左心室肥厚为NLVH组。对患者行冠脉造影 ,评估左心室功能 ,记录心电图 ,测定空腹血糖、甘油三脂和总胆固醇水平。结果　LVH组 2 9例 ( 64 .5 % )有冠脉病变 ,其中三支病变 10例 ( 2 2 .2 % ) ,病变血管重度狭窄 14例 ( 3 1.1% ) ,完全闭塞 6例 ( 13 .4% ) ,近端冠脉病变 8例 ( 17.8% ) ;NLVH组冠脉病变 3 0例 ( 3 8.9% ) ,其中三支病变 6例 ( 7.7% ) ,病变血管重度狭窄 18例 ( 2 2 .6% ) ,近端冠脉病变 6例 ( 7.7% )。两组冠脉病变程度比较差异有显著性 (P均 <0 .0 5 )。Objective To explore the relationship between the characteristic of hypertension with left ventricular hypertrophy and coronary artery disease.Methods 122 consecutive hypertensive patients with chest paia were observed and divided into two groups based on presence(LVH groups,45cases)or absence of LVH(non-LVHgroups,77cases).All patients underwent coronary angiography.LV function was assessed by echo and plasma levels of glucose,riglyceride and total cholesterol were determined.Results In LVH group,29 cases(64.5%)were confirmed as having CHD,and three-vessel disease was found in 10 cases(22.2%).The degree of stenosis was graded as sever in 14 cases (31.1%) and the lesion was located proximally in 8 cases(17.8%).In NLVH group,30 cases(38.9%) were confirmed as having CHD,three-vessel diseased were 6 cases(7.7%),the severe stenosis of lesions were 18cases(22.6%) and the proximal lesions were 6 cases(7.7%).The differences between the two groups were signifcant(P< 0.05).Conclusion Patients with hypertension and LVH may have increased occurrence rate of coronary artery disease and more severe coronary lesions.

关 键 词：高血压 左心室肥厚 冠状动脉造影 

分 类 号：R541.3[医药卫生—心血管疾病]