甲状腺超声检查及TRAb检测对Grave病复发的预测研究  

Study on the prediction of recurrence of Grave′s disease with ultrasonography and TRAb

作　　者：宋海霞[1] 哈斯[1] 牛广明 姚志清 

机构地区：[1]内蒙古医学院第二附属医院超声科,呼和浩特010059

出　　处：《放射学实践》2004年第8期612-615,共4页Radiologic Practice

摘　　要：目的 :探讨甲状腺超声检查及促甲状腺激素受体抗体 (TRAb)对Grave病 (GD)复发的预测价值。方法 :选择临床确诊的GD患者 88例作为实验组 ,以健康成人 2 0例作为对照组。所有对象均先用二维超声观察甲状腺声像图特征 ,然后用彩色多普勒血流显像观察血流动力学改变 ;同时抽取静脉血做TRAb检测。所有结果进行统计学分析处理 ,多个样本率的比较采用 χ2 检验 ,样本均数比较采用方差分析q检验。结果 :甲状腺超声检查结合TRAb检测预测GD复发的敏感度为 92 % ,特异度为 93 %。结论 :甲状腺超声检查结合TRAb检测是预测Grave病复发简便而有效的方法 ,对临床具有重要指导意义。Objective:To explore the value of the thyroid ultrasonography and TRAb measurement on the prediction of relapse of GD.Methods:88 patients confirmed as GD were divided into 3 groups and 20 healthy volunteers were studied as control group.Two dimensional ultrasonography and color Doppler ultrasonography were performed in all cases to observe the changes of the thyroid′s echography and hemodynamics.At the same time,the vein blood was drawn to determine TRAb.Statistical evaluation was carried out in all of the results.Results:The sensitivity and specificity of combination of echography and TRAb in diagnosing the relapse of GD were 92% and 93% respectively. Concluion:Combination of ultrasonography and TRAb measurement is a convenient and reliable method for predicting the recurrence of GD.

关 键 词：超声检查 TRAB检测 GRAVE病 GD 受体 甲状腺激素 

分 类 号：R581.1[医药卫生—内分泌]