骨苓通痹丸治疗地氟病临床研究  

Clinical Study on Treating Local Fluorine Poisoning by Gulingtongbi Pill

作　　者：欧亚龙[1] 王红静[2] 陈庆华[1] 唐贤俊[3] 袁明辨[4] 

机构地区：[1]四川省中医药研究院中医研究所,四川成都610031 [2]四川大学华西第二医院,四川成都610017 [3]成都军区中医药研究所,四川成都610031 [4]泸州医学院,四川泸州646000

出　　处：《中国中医药信息杂志》2004年第8期676-677,共2页Chinese Journal of Information on Traditional Chinese Medicine

摘　　要：目的 观察骨苓通痹丸治疗地氟病(痹病肝肾不足兼痰湿阻络证)疗效和临床作用机理。方法 将223例地氟病患者随机分为两组。治疗组149例以骨苓通痹丸治疗,对照组74例以维生素钙疗法治疗,观察两组疗效及治疗前后骨、血、粪、尿氟和骨X线片光密度指数的变化。结果 骨苓通痹丸治疗地氟病总有效率为94.6%,总显效率为56.4%(P<0.01);两组治疗后骨、血、粪、尿氟及骨X线片光密度指数比较,P<0.05或P<0.01。结论 骨苓通痹丸治疗地氟病疗效确切,其作用机理可能是该药有预防氟的吸收和驱氟的作用。Objective To investigate the curative effects and clinical mechanism of Gulingtongbi Pill on local fluorine poisoning (Bi syndrome, liver-kidney deficiency with phlem-dampness obstruction). Methods 223 patients of local fluorine poisoning were divided into two groups at random. 149 patients were treated by Gulingtongbi Pill, and 74 patients were vitamin-calcium therapy. The curative effects and variation of bone fluorine, blood fluorine, dung fluorine, urine fluorine, optical density index of bone X-ray films were investigated. Result As to Gulingtongbi Pill group, the total proportion of effectiveness was 94.6%, and the total proportion of producing effects was 56.4% (P<0.01). Bone fluorine, blood fluorine, dung fluorine, urine fluorine, optical density index of bone X-ray films of two groups before and after the treatment were compared, P<0.05 or P<0.01. Conclusion The Gulingtongbi Pill has definite curative effects on local fluorine poisoning. The mechanism may be restrain absorption and accelerate excretion of fluorine.

关 键 词：骨苓通痹丸 地氟病 骨氟 血氟 粪氟 尿氟 

分 类 号：R599.5[医药卫生—内科学]