复方甘草酸苷注射液治疗妊娠合并慢性乙型肝炎  

Effect of Strong Neo-Minophagen C on Chronic Hepatitis Bin Pregnant Patients

作　　者：杨珺超[1] 任潮芬 楼孝惠 屠建国[1] 徐伟[1] 王际云[1] 吴建[1] 

机构地区：[1]杭州市第四人民医院肝病科,310002 [2]杭州市江干区妇幼保健院中医内科,310016

出　　处：《医药导报》2004年第9期651-652,共2页Herald of Medicine

摘　　要：目的 :观察复方甘草酸苷注射液治疗妊娠合并慢性乙型肝炎 (乙肝 )患者的疗效。方法 :妊娠合并慢性乙肝患者共 63例 ,分为治疗组 3 3例 ,对照组 3 0例。治疗组用复方甘草酸苷注射液 80mL加入 5 %葡萄糖注射液 2 5 0mL中静脉滴注 ,qd ,4周为 1个疗程 ;对照组 :用甘草酸二铵注射液 15 0mL加入 5 %葡萄糖注射液 2 5 0mL中静脉滴注 ,qd ,4周为 1个疗程。观察患者治疗前后的临床症状及体征、胎心音、胎动情况 ;检查治疗前后肝功能、电解质、血常规、尿常规 ,血清病原学指标等。结果 :治疗组有效率 87.9% ,对照组有效率 83 .3 % ( χ2 检验 ,P >0 .0 5 )。两组均未发现不良反应。结论 :复方甘草酸苷注射液可改善妊娠合并慢性乙肝患者的肝功能 ,与甘草酸二铵注射液疗效相似。Objective:To evaluate the therapeutic efficacy of Strong neo-minophagen C (SNMC) on chronic hepatitis B in pregnant patients. Methods:Sixty-three pregnant chronic hepatitis B patien ts were divided into two groups: the treatment group (n=33) and the control group (n=30). The treatment group received SNMC injection 80ml daily for f our weeks, and the control group diammonium glycyrrhizinate injection 150 mL dai ly for four weeks. Results:The total effective rate was 87.9% in the treat ment group and 83.3% in the control group (P>0.05). The side effects were not found. Conclusion:SNMC injection and diammonium glycyrrhizinat e injection have similar therapeutic efficacy in treating pregnant chronic hepat itis B patients.

关 键 词：甘草酸苷 复方 肝炎 病毒性 乙型 慢性 妊娠 

分 类 号：R975.5[医药卫生—药品] R512.62[医药卫生—药学]