血清孕酮早期诊断异位妊娠的前瞻性临床研究  

Prospective study of early diagnosis of ectopic pregnancy by serum concentrations of progesterone

作　　者：朱前勇[1] 李力[1] 杨志玲[1] 王凤兰 姚宏[1] 

机构地区：[1]第三军医大学大坪医院野战外科研究所妇产科,重庆400042 [2]济南军区152医院,平顶山467000

出　　处：《第三军医大学学报》2004年第15期1395-1397,共3页Journal of Third Military Medical University

摘　　要：目的　确定血清孕酮早期诊断异位妊娠的临床最佳分界值。方法　将符合纳入标准的 15 6例可疑异位妊娠患者分为两组 ,孕酮组 80例采用放免法测定血清孕酮 ,非孕酮组 76例未测血清孕酮。根据两组随访结果建立受试者工作特性曲线 ,确定诊断异位妊娠的最佳血清孕酮值。结果　以血清孕酮值 <11.5ng ml诊断异位妊娠 ,其敏感性、特异性、阳性预测值、阴性预测值、阳性拟然比及阴性拟然比分别是 10 0 .0 %,76.0 %,71.4%,10 0 .0 %,4.17和 0。结论　重庆地区以血清孕酮早期诊断异位妊娠的临床最佳分界值是 11.5ng ml。Objective To determine the value of serum progesterone for the early diagnosis of patients with ectopic pregnancy (EP). Methods A total of 156 EP suspicious patients were randomly divided into two groups: progesterone group ( n =80) and non progesterone group ( n =76). The serum progesterone concentrations in patients in the progesterone group were measured and the clinical outcomes were compared with those in the non progesterone group. The receiver operator curves (ROC) were used to determine the critical serum progesterone levels for assessing the early diagnosis. Results The recommended critical level for assessing the early diagnosis for EP patients was 11.5 ng/ml according to the ROC. Conclusion Serum progesterone can be used as an index for selecting EP candidates for the early diagnosis of EP. The optimal value of serum progesterone for the early diagnosis of EP in Chongqing is 11.5 ng/ml.

关 键 词：异位妊娠 孕酮 诊断 

分 类 号：R446.11[医药卫生—诊断学] R714.15[医药卫生—临床医学]