三阶导数法测定派瑞松霜中硝酸益康唑的含量  

Determination of Econazolum Nitrate by Third Order Derivative Spectrophotometruy

作　　者：柯金珍[1] 范明霞[1] 陈一燕[1] 

机构地区：[1]厦门市第一医院,厦门361003

出　　处：《海峡药学》2004年第4期49-50,共2页Strait Pharmaceutical Journal

摘　　要：目的 　建立派瑞松霜中硝酸益康唑的含量测定方法。 方法 　采用三阶导数光谱法于 2 3 1nm,2 3 7nm等波长处测定派瑞松的含量。结果　派瑞松霜中硝酸益康唑的线性范围为 2～ 2 3 μg·m L- 1 ( r=0 .9999,n=5 ) ,平均回收率 99.0 2 % ( RSD=0 .47% ,n=6)。结论 　本方法简便、准确、快速 ,可用于产品质量控制。OBJECTIVE To determine the content of econazolum nitrate.METHODS Third derivative spectrophotometry was used.RESULTS The linear relation was obtained in the range of 2～23μg·mL -1 (r=0.9999,n=5),the average recovery was 99.02%(RSD=0.47%,n=6).CONCLUSION The method is simple accurate and rapid,it cantrol of econazolum nitrate.

关 键 词：益康唑 三阶导数 含量测定 

分 类 号：R927.2[医药卫生—药学]