深圳市宝安区膳食等因素与肾结石发病关系的随访研究  

A Follow-up Study on Dietary Factors of Kidney Stones in Bao'an District, Shenzhen City

作　　者：黎松林[1] 陈树培[1] 杨北兵[1] 吴礼康[1] 邰昌松[1] 刘益民[1] 朱元芳[1] 张朝武[2] 栾荣生[2] 袁萍[2] 

机构地区：[1]深圳市宝安区卫生防疫站,深圳518101 [2]四川大学华西公共卫生学院流行病学教研室

出　　处：《四川大学学报（医学版）》2004年第5期704-707,共4页Journal of Sichuan University(Medical Sciences)

摘　　要：目的　验证影响深圳市宝安区肾结石发病的膳食及生活习惯方面的病因假设。方法　采用调查问卷、临床和腹部 B超检查等进行肾结石的基线调查和随访研究。对基线调查的暴露资料进行相关分析、L ogistic回归分析等分析方法 ,从饮食和生活习惯、结石家族史等多个方面综合分析肾结石发病的危险因素。结果　 4 5 5 2名随访人群中 ,肾结石患者为 30 5人 ,两年累计发病率为 6 .92 %。肾结石的发病与下列因素有关 :1绝经 ,RR为 2 .4 33;2结石家族史 ,RR为 1.5 4 4 ;3海产品 ,RR(食用频率 5～ 7次 /周相对于≤ 1～ 2次 /月 )为 9.0 32 ;4新鲜水果 ,RR(食用频率≤ 1～ 2次 /月相对于≥ 1～ 2次 /周 )为 2 .2 4 9;5高糖食品 ,RR(食用频率 5～ 7次 /周相对于 1～ 2次 /周 )为 2 .5 6 8;6豆类及豆制品 ,RR(食用频率 5～ 7次 /周及≤ 1～ 2次 /月相对于 1～ 2次 /周 )分别为 2 .184及 1.6 89。结论　改变不良的生活习惯和均衡饮食 。Objective To evaluate the major dietary factors of kidney stones in Bao'an District of Shenzhen City and provide a scientific base for further effective prevention of kidney stones. Methods Following the process of stratified cluster random sampling in Bao'an district, a cross-sectional study(July-Aug, 2000) was conducted for collecting the base-line data on kidney stones from a population of permanent residents who were over 15 years old, exclusive of those who had had kidney stones or could not correctly respond to the questionnaire review. Then, a follow-up survey(July-Sept, 2002) for incident kidney stone cases was carried out among those residents. The methods for measurement included questionnaire and face-to-face interview, clinical examination and abdominal ultrasonography. All the investigators and interviewers were trained for the field work. And the data processing, dataset and analyses were performed using Visual-Fox 6.0 and SAS 6.12. The risk factors of kidney stoned were comprehensively analyzed for dietary, life style, and family history of stones. The statistical analyses included case-control comparison, factor analysis, correlation analysis, cluster analysis and logistic regression. Results There were 305 kidney stones patients among 4552 follow-up members, the cumulative incidence of 2 years was 6 92%. The kidney stones were associated with the factors: menopause, RR=2.433; family history of stones, RR=1.544; sea foods, the RR(5-7 times/week vs ≤1-2 times/month) was 9.032; fruits, the RR(≤1-2 times/month vs≥1-2 times/week) was 2.249; sweet foods,the RR(5-7 times/week vs 1-2 times/week) was 2 568; bean and bean products,the RR(5-7 times/week and ≤1-2 times /month vs 1-2 times/week) was 2.184 and 1.689. Conclusion Changing the inappropriate habitual eating patterns and generalizing the use of proportioning dietary should be the main measures to prevent kidney stones.

关 键 词：肾结石 膳食因素 随访研究 LOGISTIC 回归模型 

分 类 号：R692.4[医药卫生—泌尿科学]