10起三甲基氯化锡中毒事故及56例患者的血钾分析  

Analysis on serum potassium of 56 cases from 10 poisoning accidents caused by trimethyltin chloride(TMT)

作　　者：唐小江[1] 夏丽华[1] 赖关朝[1] 杨爱初[1] 李森华[1] 马争[1] 苏锋[1] 

机构地区：[1]广东省职业病防治院,广东广州510300

出　　处：《中国职业医学》2004年第1期11-14,共4页China Occupational Medicine

基　　金：广东省医学科学技术研究基金项目(编号 :B2 0 0 2 0 0 5)

摘　　要：目的　探讨低血钾症作为三甲基氯化锡 (Trimethyltinchloride ,TMT)中毒早期诊断、早期预防和早期治疗检查指标的价值。方法　对 10起TMT中毒事故调查资料与 56例中毒者的血清钾资料进行综合分析。结果　低血钾症是三甲基氯化锡接触者和中毒者的主要临床表现之一 ,85 7% (48/ 56)的中毒人员有低血钾症表现 ,54 5% (12 0 / 2 2 0 )的TMT接触者血钾降低。多数中毒者的低血钾症可持续 1周以上。ObjectiveTo study the practical value of h yp okalemia as an early index of diagnosis, therapy and prevention in TMT intoxicat ion. Methods The serum potassium of 56 cases exposed to TMT in 10 poisoning accidents were analyzed. ResultsHypokalemia was found to be the main clinical sign of occupational TMT exposure and intoxicatio n. The serum potassium of 48(85 7%) cases were below 3 5 mmol/L. Hypokalemia w as also found in 120(54 5%) TMT exposers occupationally. Hypokalemia could last more than a week in most of the cases. ConclusionThe availabl e evidence suggested that hypokalemia could be an early sensitive index o f TMT intoxication in workers exposed to organotin plastic stabilizer.

关 键 词：三甲基氯化锡 中毒 血钾 低血钾症 

分 类 号：R135.1[医药卫生—劳动卫生]