静滴硝酸甘油介入^(99)Tc^m-MIBI心肌显像对存活心肌的评价  

Assessment on Survival Rate of Myocardium in Infarction Region of Myocardial Infarction Patients by ^(99)Tc^m-MIBI SPECT Using Intravenous NTG Infusion

作　　者：刘保军[1] 何丽荣[1] 李娟[1] 

机构地区：[1]宁夏医学院附属医院核医学科,银川750004

出　　处：《宁夏医学院学报》2004年第4期249-250,共2页Journal of Ningxia Medical College

摘　　要：目的评价静脉滴注硝酸甘油(NTG)介入99Tcm-甲氧异丁基异腈(MIBI)心肌断层显像对心肌存活的估测价值。方法对45例心肌梗死患者先行常规静息态99Tcm-MIBI心肌断层显像,24～48h后静脉滴注NTG再行静息态心肌断层显像。结果静息态心肌断层显像检出心肌梗死灶节段111个,NTG介入后有75个梗死灶节段再填充(676%),NTG介入后梗死灶节段放射性计数为7474±8130明显较静息时(4445±6260)增大。结论静脉滴注NTG对提高静态99Tcm-MIBI心肌断层显像估测心肌存活有一定的临床价值。Objective: To compare the clinical value in assessing myocardial survival rate between the routine resting 99 Tc m-MIBI myocardial tomography and that following intravenous infusion of nitroglycerin Methods: Resting 99 Tc m-MIBI myocardial tomography imaging was performed in 45 patients with myocardial infarction, and their myocardial tomography imagings with NTG infusion process were detested 24～48 hour later Result: totally 111(27 4%,of 405) infarction segment, with hypoperfusion were found in the rest imagings of the 45 patients The improvement of perfusion after NTG infusion were revealed in 75 (67 5%) of the 111 segments Average radiation count of myocardial infarction region was increased from 44 45±62 60 by 99 Tc m-MIBI resting tomography to 74 74±81 3 by the resting tomography combind with NTG intervention The different was significant (P<0 01) Conclusion: Combination of rest 99 Tc m-MIBI myocardial tomography imaging with intravenous NTG infusion could efficiently detect the residual survival myocardium in the patient with myocardial infarction

关 键 词：心肌梗死 放射性核素显像 硝酸甘油 心肌存活 单光子发射计算机断层成像 

分 类 号：R817.4[医药卫生—影像医学与核医学]