卟吩类化合物对果腹果蝇的光活化毒力  

Phototoxicity of porphyrins toward drosophila melanogaster

作　　者：李玥[1] 陈志龙[1] 王建国[1] 

机构地区：[1]第二军医大学海医系毒物药物研究室,上海200433

出　　处：《中国公共卫生》2004年第9期1027-1028,共2页Chinese Journal of Public Health

基　　金：国家自然科学基金资助项目 (2 9872 0 55;30 0 70 862;30 2 71 534)

摘　　要：目的　测定卟吩类化合物 -四 - (3’ -甲基 ) -苯基卟吩 (TMPP)对果腹果蝇的光活化毒性。方法　果腹果蝇随机麻醉分组 ,每组 2 0只 ,根据处理方法进食不同培养基 ,以焦脱镁叶绿酸a(Pa)为阳性对照品 ,选择适当的浓度 ,测定不同处理方式、光照时间长短和光照强弱对毒效的影响。结果　TMPP的光活毒杀效应随化合物浓度的提高、光照时间的延长及强度的增加而增强。相同条件下 ,TMPP的活性比Pa强。结论　光和光敏剂是光活化杀虫效应的关键 。Objective To investigate the phototoxic activity of tetra-(4-methyl)phenyl-porphine(TMPP)toward drosophila melanogaster.Methods The flies were randomly grouped with 20 flies in each by ether anesthesia.The response of flies to irradiation was determined as by the following parameters:TMPP concentration in the bait (0.5-2.0?g/L);irradiation time (1-2?h);and irradiation intensity(one or two 40 W electric incandescent lamps).Results It was showed that the mortality of the TMPP-fed flies to light was increased with the increase of TMPP concentration in the bait,the extending of irradiation time and the elevating of irradiation intensity.Under the same condition,TMPP showed stronger phototoxic activity than Pa.Conclusion TMPP was a favorable photosensitizer and can be used for insect control.Light played an important role in its phototoxicity.

关 键 词：卟吩类化合物 光活化杀虫剂 光敏剂 

分 类 号：S482.3[农业科学—农药学]