抗HBs-抗独特型抗体与各型乙肝病毒感染者的关系  

RELATIONSHIP BETWEEN ANTI IDIOTYPE ANTIBODY AGAINST ANTI-HBS AND INDIVIDUALS OF DIFFERENT HBV INFECTION

作　　者：冯婥[1] 蒋自钟[1] 何少璋[1] 徐建英[1] 

机构地区：[1]广州医学院第二附属医院传染病科

出　　处：《广东医学》1993年第3期131-132,共2页Guangdong Medical Journal

摘　　要：目前已知免疫系统包括一个独特型网络,并且独特型及抗独特型抗体在免疫调控网中起重要作用。Auti-idiotype antibody against anti-HBswas determined in 133 individuals of HBVinfection The prevalence of such anti-Id anti-bodies in sera from asymptomatic HBV carri-ers, and chronic active hepatitis, and chronicpersistent hepatitis, and acute viral hepatitiswere 46.15%, 32.50%, 25.53% and 12.12%respetively. 62.07% cases(18/29) of bothHBeAg and Pre-S_2-Ag positive were anti-Id-anti-HBs positive whereas 12. 12% cases(4/33) of both HBeAg and HBV.DNA negativewere anti-Id-anti-HBs positive. It was confi-rmed that the presence of anti Id-anti-HBrmight be correlated with serologic evidence ofHBV replication and played an important rolein the chronicity of HBV infection.

关 键 词：乙型肝炎 抗独特性 抗体 

分 类 号：R512.620.3[医药卫生—内科学]