合成1-氨基环丁甲酸的新方法  

A novel synthesis route of 1-aminocyclobutanecarboxylic acid

作　　者：徐景海[1] 冷延国[1] 付志峰[1] 

机构地区：[1]北京化工大学材料科学与工程学院,北京100029

出　　处：《化工科技》2004年第3期30-32,共3页Science & Technology in Chemical Industry

摘　　要：以乌洛托品为催化剂,向1 溴代环丁甲酸的异丙醇溶液中通入氨气,在回流条件下制备出1 氨基环丁甲酸。较原文献所载方法不仅合成路线比较短,而且操作也更容易,具有良好的应用前景。1-Aminocyclobutanecarboxylic acid was prepared by reacting ammonia gas with 1-bromo-cyclobutanecarboxylic acid in presence of hexamethylenamine.The route was more convenient and practical than one previously.A novel and practical method for the synthesis of 1-aminocyclobutanecarboxylic acid was developed and showed industrial application prospect.

关 键 词：乌洛托品 1-溴代环丁甲酸 异丙醇 氨气 合成方法 1-氨基环丁甲酸 溴代反应 

分 类 号：TQ225.1[化学工程—有机化工]